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Nuclera
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  • Senior Embedded Software Engineer  

    - Cambridge
    Nuclera is a venture-backed biotech company headquartered in Cambridge... Read More
    Nuclera is a venture-backed biotech company headquartered in Cambridge, UK with significant operations in Boston, USA. Nuclera’s mission is to accelerate discovery by enabling rapid, easy access to functional proteins essential for drug discovery research. Our eProtein Discovery™ benchtop system accelerates protein expression and purification optimization in research labs.As a Senior Embedded Software Engineer, you will be a key contributor to the development of our cutting-edge instrument platform. You will take ownership of the design and implementation of complex embedded systems, from low-level hardware interaction to high-level application logic. This role requires a versatile engineer who is comfortable working across different domains, including bare-metal firmware, RTOS, and embedded Linux, to build a reliable, scalable, and high-performance system.About the role Architect, develop, and maintain real-time bare-metal and RTOS-based firmware for ARM cores, ensuring robust control of hardware peripherals. Develop and optimize low-level drivers for communication protocols including SPI, I2C, UART, USB, and Ethernet. Oversee the full lifecycle of mixed-signal PCBA development, from requirements and component selection to schematic capture, layout, and vendor management. Design and implement software for advanced System-on-Chip (SoC) platforms, ensuring seamless integration between processors and programmable logic. Develop multi-threaded C/C++ applications on embedded Linux for system control, data processing, and communication with other system components. Implement and optimize complex algorithms for signal processing and real-time control. Lead board bring-up, debugging, and hardware-software integration efforts. Implement and maintain CI/CD pipelines for embedded software delivery and contribute to production software tooling. RequirementsEssentials: Bachelor's or Master's degree in Computer Science, Electrical/Electronic Engineering, or a related field. 5+ years of professional experience in embedded software development. Expert proficiency in C and C++ for bare-metal, RTOS, and embedded Linux environments. Strong experience with Embedded Linux (e.g., Yocto) and real-time operating systems. Proven experience in board bring-up, hardware-software integration, and debugging using tools like oscilloscopes, logic analyzers, and JTAG/SWD. Proficiency in Python for scripting, tooling, or testing. Proficiency with version control (Git) and familiarity with CI/CD workflows. Advanced knowledge of hardware-software interaction and communication protocols. Desirable: Experience in the life sciences, biotech, or medical device industries. Experience with schematic capture and PCB layout tools (e.g., Altium, KiCad, Eagle). Experience with embedded systems that incorporate image processing or machine learning. Development of desktop or embedded GUI applications (e.g., using Qt). Familiarity with cloud-connected embedded systems and backend integration. Knowledge of standards and regulations relating to EMC and safety for electronics. BenefitsWhat we offer:In addition to competitive salaries, we offer a range of benefits including: Company bonus scheme of 5% Life insurance Private medical insurance and cash plan 25 days' annual leave + Bank Holidays Enhanced employer's pension contributions Enhanced maternity and paternity Leave Investment in professional development and learning Access to amenities on Vision Park and in Histon Fresh fruit, tea, coffee, and snacks in the office Organised team events Read Less
  • Director of Product Management - Protein Science  

    - Cambridge
    Nuclera is a venture-backed biotech company headquartered in Cambridge... Read More
    Nuclera is a venture-backed biotech company headquartered in Cambridge, UK with significant operations in Boston, USA. Nuclera’s mission is to accelerate discovery by enabling rapid, easy access to functional proteins essential for drug discovery research. Our eProtein Discovery™ benchtop system accelerates protein expression and purification optimization in research labs.Nuclera is seeking a dynamic, high-energy, and results-driven Director of Product to champion the launch and expansion of a groundbreaking product in the life sciences market. This is a unique opportunity to join a trailblazing biotech company that is revolutionizing rapid protein expression and purification workflows, where innovation moves at an extraordinary pace.  Unlike overseeing a mature product portfolio with incremental updates, the Director of Product must provide strategic leadership and work hand-in-glove with our target customers—guiding the rapid evolution of our eProtein Discovery platform to ensure it’s fit-for-purpose and drives strong market adoption.At the heart of Nuclera’s eProtein Discovery System lies a sophisticated integration of instrumentation, digital microfluidics cartridges, customized reagents, and software—a combination that delivers efficiency and automation to our customers while bringing uniqueness, complexity, and excitement to the Product team.The ideal Director of Product thrives in a high-velocity, change-intensive environment, acting as a strategic liaison between our customers, the commercial organization, and internal R&D.The ideal candidate must be a seasoned protein scientist with proven commercial experience, deeply versed in the pain points, challenges, and opportunities of the protein landscape—and adept at harnessing robust voice-of-customer insights to drive the market success of our eProtein Discovery System.This role requires approximately 25-30% travel, including domestic and international trips, to attend customer meetings, industry events, and visits to office as needed. Key responsibilities:  Strategic Product Leadership:
    Own the end-to-end product lifecycle—from vision and roadmapping through launch and scale—ensuring alignment with Nuclera’s strategic objectives, revenue goals, and evolving market demands. Mentor and oversee product managers to drive consistent, high-impact delivery. Market Intelligence & Customer Insight:
    Lead rigorous, ongoing market research and VOC programs (surveys, in-depth interviews, advisory boards) to surface unmet needs in protein science. Translate these insights into prioritized feature investments and clear business cases that inform the product roadmap. Cross-Functional Leadership & Stakeholder Management:
    Serve as the senior liaison between external stakeholders (customers, KOLs, sales, marketing) and internal teams (R&D, operations, quality, finance). Champion product requirements, secure executive buy-in, and ensure transparent communication on priorities, timelines, and metrics. Organizational Agility & Change Management:
    Navigate the complexities of a high-velocity startup environment—spotting risks early, realigning resources on shifting priorities, and driving continuous improvement in processes (e.g., agile ceremonies, OKRs, KPIs) to maintain momentum and resilience. Additional responsibilities: Champion the Voice of the Customer at the Executive Level: Advocate relentlessly for customer and commercial-team needs across instrumentation, microfluidics, software, and reagents—ensuring these insights drive your strategic roadmap and influence executive decisions. Elevate Strategic User Experience: Set the bar for our instruments and cloud-based software, defining UX standards and guiding  teams to deliver intuitive, delightful experiences that boost adoption and retention. Drive Innovation & Commercial Viability: Lead high-impact product initiatives by combining primary VOC programs with secondary market research—translating deep customer understanding into prioritized feature sets, robust business cases, and clear financial models. Develop Strategic Plans & Business Cases: Architect and own comprehensive business plans, go-to-market strategies, and detailed user requirements for new product launches, aligning cross-functional teams and securing executive buy-in. Monitor Competitive & Industry Trends: Proactively scan the drug discovery, protein, CFPS, and broader life-science tools landscape—delivering actionable insights and trend analyses to keep Nuclera ahead of the curve. Cultivate Strategic Partnerships with Thought Leaders: Build and steer high-impact relationships with Key Opinion Leaders (KOLs), academic and industry collaborators, and channel partners—co-developing new applications and pioneering use cases that expand and differentiate our eProtein Discovery platform. RequirementsEssential: 10+ years of life science/biotech product management experience, including 2+ years in a leadership role Demonstrated leadership: Proven track record building and mentoring product teams, setting strategy, and driving cross-functional execution Advanced life-science degree (PhD preferred; MSc/MBA acceptable with equivalent experience) with significant industry experience Deep antibody expertise: Hands-on experience in protein expression and purification workflows, with a strong grasp of CFPS and related technologies Commercial acumen: History of translating scientific insights into compelling product offerings that achieve strong market adoption and revenue targets Influence & communication: Exceptional ability to align stakeholders—from bench scientists to executives—through clear, persuasive storytelling of complex scientific concepts Voice-of-Customer mastery: Skilled at designing and running VOC programs, synthesizing feedback into prioritized roadmaps and robust business cases

    Desirable: Experience in pharma/biopharma environments, particularly launching protein-focused tools or reagents Background in managing both scientific software and hardware instrumentation Prior work in high-growth startup settings BenefitsWhat we offer:In addition to competitive salaries, we offer a range of benefits including: Company bonus scheme of 5% Life insurance Private medical insurance and cash plan 25 days' annual leave + Bank Holidays Enhanced employer's pension contributions Enhanced maternity and paternity Leave Investment in professional development and learning Access to amenities on Vision Park and in Histon Fresh fruit, tea, coffee, and snacks in the office Organised team events Read Less
  • Lead Software Quality Assurance Engineer  

    - Cambridge
    Nuclera is a venture-backed biotech company headquartered in Cambridge... Read More
    Nuclera is a venture-backed biotech company headquartered in Cambridge, UK with significant operations in Boston, USA. Nuclera’s mission is to accelerate discovery by enabling rapid, easy access to functional proteins essential for drug discovery research. Our eProtein Discovery™ benchtop system accelerates protein expression and purification optimization in research labs. We are seeking a highly motivated and experienced Lead Software Quality Assurance (QA) Engineer to define and drive our testing strategy, lead our QA team, and ensure the highest standards of software quality for our groundbreaking eProtein Discovery platform. Join us in shaping the future of protein prototyping technology. As a QA Team Leader, you’ll bring strong leadership skills, a deep understanding of modern test automation frameworks, and hands-on experience with Javascript and Python coding in frameworks like Cypress and Playwright. You will play a vital role in ensuring the quality, performance, and reliability of both our cloud-based and on-instrument software. While no prior biology background is required, curiosity and a willingness to learn are essential.  This role will be primarily working onsite in our Cambridge, UK office with occasional work remotely from home.  About the role Maintain, expand, and improve our automated test suites across both instrument and cloud platform Write detailed bug reports, including clear reproduction steps and relevant evidence (logs, screenshots, videos) Champion a quality-first mindset across the engineering organization by promoting best practices such as early test involvement and developing with testability in mind Collaborate and regularly communicate with the Nuclera Quality team, product managers, engineers, and other stakeholders to define and implement robust QA strategies for web applications and connected devices Provide clear and actionable test evidence to stakeholders to demonstrate compliance with quality standards Line manage and support junior and mid-level QA engineers through mentorship and training RequirementsEssential:  4+ years of hands-on experience in both manual and automated software testing,  Strong proficiency in Javascript and Python coding with automated testing frameworks such as Cypress, Playwright, or similar tools Demonstrated experience designing and executing risk-based testing strategies, and effectively communicating quality risks to technical and non-technical stakeholders Proficiency with version control systems (e.g., Git) and collaboration in Git-based workflows Familiarity with CI/CD pipelines (e.g., GitLab CI, Jenkins) and integrating automated tests into development workflows  Solid understanding of Linux environments and command-line tools (e.g., bash, ssh, package managers) Proven track record of working in Agile/Scrum development teams, including close collaboration with product and engineering teams Excellent communication and documentation skills, including the ability to write clear bug reports and actionable test evidence  Desirable: 1–2 years in a QA leadership or mentoring capacity Experience testing connected devices such as networked laboratory instruments, IoT devices, or embedded systems Familiarity with non-functional testing areas, including performance, stress, and scalability testing Exposure to quality methodologies such as CAPA (Corrective and Preventive Actions), 8D Problem Solving, or Six Sigma Ability to contribute to test strategy documentation and quality-related process improvements across cross-functional teams Familiarity with software security testing principles, including understanding of vulnerabilities and how to test for them BenefitsWhat we offer:In addition to competitive salaries, we offer a range of benefits including:Company bonus scheme of 5% Share option incentive scheme  Life insurance  Private medical insurance and cash plan  25 days' annual leave + Bank Holidays  Enhanced employer's pension contributions  Enhanced maternity and paternity Leave  Investment in professional development and learning  Fresh fruit, tea, coffee, and snacks in the office  Organised summer events for staff Read Less
  • Research Associate - Service Fulfillment  

    - Cambridge
    Nuclera is a venture-backed, founder-driven biotech company headquarte... Read More
    Nuclera is a venture-backed, founder-driven biotech company headquartered in Cambridge, UK with significant operations in Boston, USA. The company’s mission is to improve human health by making proteins accessible. We are beginning this mission through the launch of our eProtein Discovery™ platform. eProtein Discovery is a breakthrough protein expression, characterization, and purification technology, consisting of a lab-based benchtop instrument, cloud-based software and proprietary cartridges and consumables. The goal is to enable rapid protein access to life science researchers around the world.The successful candidate will be responsible for amplifying DNA constructs as well  as designing, delivering and analyzing custom projects using our eProtein Discovery Platform in strict accordance with SOPs and work instructions.  This position requires the ability to deliver under tight deadlines, attention to detail and strong organizational skills while working independently in a fast-paced environment. The ideal candidate will have a strong background in molecular biology, protein science, or a related discipline, with proven hands-on experience in an industry setting.About the role: Perform PCR to prepare DNA constructs for cell-free protein expression. Carry out protein purification, quantification and SDS PAGE analysis. Design, execute and analyze  experiments using Nuclera’s eProtein Discovery Platform. Adhere strictly to Work Instructions and Standard Operating Procedures to ensure consistency and quality. Systematically organize, track and manage large numbers  of biological samples. Accurately record and document experimental methods, observations and results. RequirementsEssential  BSc in biochemistry, molecular biology, or a related discipline, with a minimum of 3 years’ industry experience  Proven track record of generating reliable data and delivering results within tight deadlines. Hands-on experience in molecular biology techniques including PCR, PCR clean-up and agarose gel electrophoresis. Experience with protein science techniques, including affinity-based purification, protein quantification and SDS PAGE analysis. Strong organizational skills. Eligible to work in the UK. Desirable MSc in biochemistry, molecular biology, or related discipline, with a minimum 2 years’ industry experience  Previous experience in a Contract Research Organization (CRO) and/or the biotechnology industry. Familiarity with liquid handling platforms such as Tecan and KingFisher. Experience using automated electrophoresis systems such as the. Fragment Analyzer. Understanding of the principles of cell-free protein synthesis technologies. BenefitsWhat we offer:In addition to competitive salaries, we offer a range of benefits including: Company bonus scheme of 5% Life insurance Private medical insurance and cash plan 25 days' annual leave + Bank Holidays Enhanced employer's pension contributions Enhanced maternity and paternity Leave Investment in professional development and learning Access to amenities on Vision Park and in Histon Fresh fruit, tea, coffee, and snacks in the office Organised team events Read Less
  • Scientist - Service fulfillment  

    - Cambridge
    Nuclera is a venture-backed, founder-driven biotech company headquarte... Read More
    Nuclera is a venture-backed, founder-driven biotech company headquartered in Cambridge, UK with significant operations in Boston, USA. The company’s mission is to improve human health by making proteins accessible. We are beginning this mission through the launch of our eProtein Discovery™ platform. eProtein Discovery is a breakthrough protein expression, characterization, and purification technology, consisting of a lab-based benchtop instrument, cloud-based software and proprietary cartridges and consumables. The goal is to enable rapid protein access to life science researchers around the world.The successful candidate will design, analyze, troubleshoot and deliver custom projects using our eProtein Discovery Platform. This role requires the ability to manage multiple projects independently in a fast-paced environment, while maintaining attention to detail and strong organizational skills. The ideal candidate will troubleshoot experiments and clearly communicate the results through well-documented reports and presentations. They will have a strong background in molecular biology, protein science, or a related discipline, with proven hands-on experience in an industry setting.About the role: Execute and analyse experiments using Nuclera’s eProtein Discovery Platform to ensure successful and timely delivery of customer projects. Contribute to the design of experiments to optimise outcomes. Collaborate with the team to troubleshoot and resolve experimental challenges. Manage multiple projects in parallel, maintaining high standards of quality and efficiency. Follow Work Instructions and Standard Operating Procedures to ensure consistency, compliance, and reproducibility. Communicate findings effectively through well documented reports and presentations. RequirementsEssential: BSc in Protein Science, Biochemistry, Molecular Biology, or a related field, with a minimum of 4 years’ industry experience or MSc with 3 years’ industry experience  Demonstrated capability of managing and delivering multiple projects in parallel. Hands-on experience in common molecular biology techniques, including PCR, PCR clean-up and agarose gel electrophoresis.  Experience with protein science techniques, including protein expression, affinity-based purification, protein quantification and SDS PAGE analysis. Eligible to work in the UK. Desirable: PhD in Protein Science, Biochemistry, Molecular Biology, or related field with a minimum 1 years’ industry experience  Experience operating liquid handling robots such as Tecan and KingFisher. Understanding of the principles of cell-free protein synthesis technologies. Experience in protein engineering, including structure-guided design of protein variants for enhanced stability, activity, or yield. Experience with protein characterisation techniques such as Size Exclusion Chromatography (SEC). BenefitsWhat we offer:In addition to competitive salaries, we offer a range of benefits including: Company bonus scheme of 5% Life insurance Private medical insurance and cash plan 25 days' annual leave + Bank Holidays Enhanced employer's pension contributions Enhanced maternity and paternity Leave Investment in professional development and learning Access to amenities on Vision Park and in Histon Fresh fruit, tea, coffee, and snacks in the office Organised team events Read Less

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