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• 

  Electronics Engineer  

  Medical Research Council

  [fulltime] - Cambridge

  Posted: 24/12/2025

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  Key responsibilities:Responsible for the design, production and develo... Read More

  Key responsibilities:Responsible for the design, production and development of electronic equipment and instrumentation to meet the needs of the science in an innovative and flexible way and conforming to all statutory and local health and safety regulations.Designing electronics circuitry, developing the embedded or PC control software and converting this to hardware including the design and layout of circuit boards, manufacturing all the required infrastructure, and carrying out any testing and debugging.Consulting with engineers from the Mechanical Workshop where necessary in developing workable solutions to problems in an efficient and timely manner.Keeping abreast of technological developments to ensure that advice given on possible solutions to challenges is based on an up to date knowledge of leading-edge technology.Providing a high level of electronics and software expertise to scientific staff in order to develop novel protocols and methods not available with existing commercial equipment.Ensuring that work is suitably documented.Working relationships:The role reports directly to the Head of the Electronics Workshop. The Workshop, which is part of the Structural Studies Division, is also staffed by two Senior Electronics Engineers and an Electronics Technician.On a day to day basis, the role deals directly with Scientific Staff and works closely with other departments concerned with technical support including the Engineering Workshop, the IT department and Instrument Services. /*generated inline style */ Person Specification Education / qualifications / training required:Essential:Degree or HND level qualification in an engineering discipline.Previous work experience required:Essential:Extensive experience in high level electronics-based design, including analogue & digital techniques and PCB layout.Experience of software development in C for embedded systemsTechnical knowledge regarding the latest developments in electronics.Desirable:Experience of instrumentation design in a scientific environment, in particular with sensor technology and low noise measurement techniques.Experience of data acquisition using LabVIEWExperience of programming for Windows/Linux applications in C and Python.Knowledge and experience: Creativity and initiativeEssential:Track record in providing innovative solutions to diverse design challenges.Desirable: The ability to approach problems with creativity and an open mind.Knowledge and interest in Arduino, Raspberry Pi, making things etc.Independent workingEssential: The ability to work safely without close supervision.The ability to take on and see a project through from start to completion, coupled with experience in project management and systems design.Verbal and written communication skillsEssential:The ability to communicate with other staff at all levels, and able to create clear and precise documentation.Personal skills / behaviours / qualities: Essential: A mature and conscientious attitude.Ability to approach problems in a creative manner and to suggest engineering solutions to scientific questions.Strong organisational skills with the ability to prioritise work to deal with several projects simultaneously. Working to strict deadlines, whilst providing accurate information.Desirable: An inquisitive nature with regard to finding engineering solutions to challenges and a desire to understand the work of the department and how it relates to the science carried out in the LMB. /*generated inline style */ Read Less

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• 

  Study Manager  

  Medical Research Council

  [fulltime] - Didcot

  Posted: 19/12/2025

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  Overall purpose: To oversee management of studies as part of the in vi... Read More

  Overall purpose: To oversee management of studies as part of the in vivo team in the Mary Lyon Centre (MLC) at MRC Harwell.This post would be responsible for executing studies planned by the in-vivo project managers for external academic researchers or biotech companies. These studies involve mouse models of human diseases, including cancers, mitochondrial disease, kidney disease and other areas. Most studies involve phenotyping tests, dosing and welfare assessment, followed by tissue dissection after study termination.This role requires excellent organisation skills to plan studies across teams, organise workflows and ensure work is completed on time and of high quality. This role is also a critical step in the quality control process, ensuring that day-to-day changes in the study plan are well thought out and appropriate, and that detailed records are kept and reported back to senior managers and researchers. Whilst the post-holder will need to carry out some procedures, such as dosing and tissue dissection, the primary purpose of this post is organisation and record keeping.The post-holder will line manage a team of two technicians who will carry out many of the dosing and imaging experiments and will liaise closely with other managers and teams of technicians who work together to complete these studies.
  Main duties/key responsibilities: Line Management Line management of technicians working in the in vivo projects team, including pastoral care, career development, managing performance etc.Study ManagementDay-to-day responsibility for running allocated studies, which includes scheduling mouse cohorts, arranging technicians to cover tests, calculating doses and diluting drugs, organising appropriate training, ensuring that full plans are in place and that relevant paperwork ( risk assessments and SOPs) is signed off by techniciansAllocate workload of technicians under direct line management, as well as discussing with other managers to ensure distribution of workload across teamsDevelop SOPs and ensure these are read and adhered toTroubleshoot problems that arise in studies, using your experience to make appropriate judgment on the best course of actionWork flexibly to manage changing priorities in a busy working environmentGenerate study records and ensure that they are up to date and accurateEnsure that all studies are compliant with Home Office regulations; , that they are covered by the Project Licence and that technicians working on the study are licenced, trained and competentWork alongside other managers in the MLC to ensure that mice are appropriately looked after and welfare is taken care of as a priorityCarry out basic plotting to check data such as mouse body weights vs treatmentCarry out quality control of data relevant to your studies, helping the data management and project management teams to ensure that all data is complete and correctAdvisory role / responding to enquiriesLiaise with internal and external users in response to enquiries about studies under your supervisionTrainingUndergo training to achieve a Home Office Licence to allow work on miceCarry out training of technicians, particularly in good laboratory skills, making up solutions and calculating dosesWorking relationships: The post-holder will work within the in vivo projects team and will be line managed by the In Vivo Project Manager. They will work closely with 8-9 other managers; together these managers look after all the teams working with mice in the Mary Lyon Centre and share resources to get the studies done. This requires someone with excellent teamwork skills and the ability to build good working relationships and support both their own team and the teams they work alongside. /*generated inline style */ Person Specification Education/Qualifications/Training Required: Essential:Master’s degree or a bachelor’s degree, with extensive biological experience in an academic or commercial research setting.Desirable:Home Office licencePrevious Work Experience Required: Essential:Extensive research experience, including working in a laboratory environmentStudy or project managementDesirable: Experience of working with any laboratory animalsExperience of working under the Animals (Scientific Procedures) Act 1986Knowledge and Experience: Essential:Proficient in the use of Microsoft packagesAbility to accurately follow protocols/SOPsAbility to calculate concentrations and dosesExperience in accurate record keeping for multiple studiesDesirable:Experience with laboratory information management systemsExperience of writing SOP’sExperience of quality control processesPersonal skills/Behaviours/Qualities: Essential:Excellent communication skillsExcellent attention to detailFlexible and adaptable in approach to work to ensure changing priorities and deadlines are metA service-delivery focusAbility to work on day-to-day functions both independently and as part of a teamDesirable: Experience in training others /*generated inline style */ Read Less

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• 

  Biological Samples Shipping Coordinator  

  Medical Research Council

  [fulltime] - Didcot

  Posted: 15/12/2025

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  Overall purpose: The Biological Samples Shipping Coordinator role will... Read More

  Overall purpose: The Biological Samples Shipping Coordinator role will support Harwell’s standing as a national/international centre for mouse resources. Our clients include an extensive network of UK collaborators and overseas clients. The primary function of this role will be to coordinate the exportation of biological materials to the scientific community around the world. The post-holder will work within the Laboratory Services team and will work closely with other departments to maximise operational efficiency. Experience within an outward-facing environment, customer service or administration role would be ideal. This role will suit a person who has an aptitude to learn and the passion to grow, as full training and support will be provided. The post-holder will need to be a team player, customer focused, possess excellent communication skills, and have a keen eye for detail.Main Duties/Key Responsibilities: Working within a team environment at the Mary Lyon Centre (MLC), Harwell, the post-holder’s principal responsibility will be to support the processes involved in shipping biological samples from MRC Harwell. Examples of the type of activity this may involve are:Physically locating and packing biological samples before shipment (including packaging on dry ice and liquid nitrogen)Working with other members of staff dedicated to dissemination of resources and assisting them as and when necessaryLiaising with investigators within the MRC and other universities/institutes to coordinate the dissemination of biological samplesVerifying the details of shipments being sent outBuilding relationships and liaising with courier companies to ensure the safe delivery of shipmentsEnsuring that the quality and accuracy of our delivery services are maintainedOther inventory management tasksWorking Relationships: The post-holder will report directly to the Head of Laboratory Services and will be expected to develop and maintain good working relationships with other departments, as well as scientific staff at all levels, to optimise information flow and understanding of all requirements. The post-holder will also need to independently develop professional working relationships with clients and shipping organisations.Other Information:The post-holder is expected to play an active role in improving the effectivity and efficiency of biological sampling management and coordinating the exchange of resources between MRC Harwell and the wider scientific community. This post is suited to someone who is a committed team player and who is flexible and happy to embrace work at all levels. They should also be prepared to interact with a wide variety of people to bring projects to a successful conclusion within the required timeframe. /*generated inline style */ Person Specification Education/Qualifications/Training Required: Essential:GCSE maths and English Desirable:HNC or equivalent in a science subjectPrevious Work Experience Required: Essential: Previous experience in an environment involving a wide range of outward-facing activities and/or administrative tasks Desirable: Experience of working in a biological environment in which goods and services are exchanged within an academic or commercial organisationKnowledge and Experience: Essential: Ability to work in a fast-paced, high-throughput service roleAbility to work within a multi-disciplinary teamAbility to understand/use IT packages and databases at an Intermediate levelDesirable: Experience in the importation/exportation of biological or other materialsKnowledge of shipping regulations by land, air and sea or the willingness to attend trainingExperience of using a laboratory Information Management System (LIMS)Personal skills/Behaviours/Qualities: Essential: Excellent communication and interpersonal skills (verbal and written)Self-motivated, with good time-management skillsAbility to prioritise tasks efficientlyCan apply imagination and independent thinking to a variety of challengesGood attention to detailAbility to work independently and use initiative to resolve problemsCommitment to providing good customer serviceDesirable: A proven ability to work to tight deadlines within a busy environmentAbility to deal with a wide range of people from different disciplines and at various levels in an organisation /*generated inline style */ Read Less

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• 

  Maintenance Engineer  

  Medical Research Council

  [fulltime] - Cambridge

  Posted: 03/12/2025

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  Key responsibilities:• Providing planned and preventive maintenance (P... Read More

  Key responsibilities:• Providing planned and preventive maintenance (PPM) and reactive maintenance (RM) on plant systems and services.• Undertaking works on behalf of the Estates & Facilities team including supervising external service providers and contractors.• Liaising with end users to plan maintenance works or project works as required.• Operating the computer-controlled Building Management Systems (BMS) to monitor and identify fault diagnostics, taking the appropriate action to resolve these.• Overseeing the operation of the steam boilers and systems. Steam is used extensively throughout our sites and training will be given as required.• Assisting with the training and mentoring of apprentices.• On-call duties approximately 6-8 weeks per annum on a rota basis, responding to callouts when off-site, including weekend. You will receive an additional payment when on-call/call out.Working relationships:Reporting to the Services Coordinator and part of the Estates and Facilities team.Interacting with external service providers and contractors.  /*generated inline style */ Person Specification Education / qualifications / training required: Essential: 
  • Completed a recognised electrical or mechanical apprenticeship or hold the equivalent qualification.
  • Full UK driving licence holder.
  • Must live within a 30 mile radius in order to reach sites in a reasonable time when on-call/call out.Desirable: 
  • Experience of completing risk assessments for work activities.
  • Formal training/qualifications relating to steam boilers, including analysis of steam systems and boiler water treatment.
  • Boiler Operation Accreditation Scheme (BOAS) certificate.Previous work experience required: Essential:
  • Experience of working in a complex building with responsibility for electrical or mechanical systems.Knowledge and experience: Essential: 
  • Good working knowledge of engineering services coupled with a good understanding of all aspects of building maintenance.
  • Experience of using a Building Management System (BMS).
  • An understanding of Heating, Ventilation, and Air Conditioning (HVAC) systems.
  • Competent IT user.Desirable: 
  • An understanding of statutory maintenance requirements.Personal skills / behaviours / qualities: Essential: 
  • Excellent interpersonal skills with the ability to work closely and effectively with staff at all levels.
  • Ability to plan and prioritise work without or under limited supervision.
  • Ability to use initiative when required. /*generated inline style */ Read Less

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• 

  MRC Postdoctoral Research Scientist LMS 2729  

  Medical Research Council

  [fulltime] - London

  Posted: 20/11/2025

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  Overall purpose: The postdoctoral researcher will join a multi-discipl... Read More

  Overall purpose: The postdoctoral researcher will join a multi-disciplinary team working on a multi-lab team science initiative aimed at understanding and modulating cytosolic nucleic acid sensing pathways involved in chronic inflammation and ageing (“inflammageing”). The successful candidate will integrate expertise in culture of primary cells and organoids, knowledge on molecular, cellular biology, immunology and functional screens.The postholder will employ a combination of cellular systems of senescence and develop assays to evaluate the effect of nucleic acid sensing pathways ( cGAS/STING, RIG-I, MDA5 and others) using functional genomics on senescent phenotypes and the interaction of senescent and immune cells. As part of the project, the postholder will develop sophisticated co-culture systems to evaluate the interaction of senescent and immune cells in the context of ageing.The postholder will be supervised by Prof. Gil (Senescence group) and Prof. Brodin (systems Immunology). More broadly, this post is part of a Institute wide collaboration and the postholder will be tightly coordinated and involved in meetings with other PIs and researchers working in the project.
  Main duties / key responsibilities: Establish novel cell systems to study senescence (using primary cells and organoids) relevant for ageingEstablish systems to study the interaction between senescence and immune cellsPerform functional screens and assays (using RNAi, CRISPR and drugs) to assess the role of nucleic acid sensing pathwaysDevelop and optimise cell culture assays to assess the interaction between immune and senescent cells and evaluate the effect of different perturbationsCollaborate with other scientists to investigate candidates in preclinical models and clinical samplesProvide training and support to junior lab members, including PhD studentsParticipate in regular lab meetings, journal clubs, and institute seminarsWrite scientific papers and present findings at national and international conferencesTake an active part in the academic activities of the LMSForm good working relationships with other members of LMS groups as well as internal and external collaborators /*generated inline style */ Person Specification Education / Qualifications / Training required (will be assessed from the application): Essential:PhD in Cell Biology, Molecular Biology, or ImmunologyDesirable:Knowledge on senescenceKnowledge on immunology
  Previous work experience required (will be assessed from the application and at the interview): Essential: Good written communication skills in EnglishExtensive cell culture experienceExperience with functional genomics (CRISPR, RNAi)Track record of publishing scientific results in peer-reviewed journals, including a first-author paperDesirable: Experience with high-throughput screeningExperience in high content microscopyExperience with organoid, 3D or co-culture systems
  Personal skills/behaviours/qualities (will be assessed at the interview):Essential: Excellent laboratory skillsExcellent organisational skillsExcellent attention to detailsExcellent creativityHigh-Motivation and perseveranceThe post holder should be prepared to work unsociable hours as work demands from time to timeAbility and willingness to adapt to changing timetables or work patterns as dictated by changing circumstancesAbility to work under pressure while maintaining a high degree of accuracyProven ability to prioritise, plan ahead and manage a high volume of work to meet deadlines, both prescribed and self-imposedAbility to use own initiative and work independently and as part of a team, as requiredProblem solving abilitiesProven multitasking abilitiesAbility to work in a collaborative research environmentWillingness to give and receive help with challenging problemsGood verbal communication skills in EnglishAbility to communicate its science in a clear wayGood interpersonal skillsWillingness to share knowledge and transfer skills to other members of the group on a daily basis /*generated inline style */ Read Less

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• 

  Postdoctoral Scientist  

  Medical Research Council

  [fulltime] - Cambridge

  Posted: 13/11/2025

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  Key responsibilities:Within the overall direction of the programme, th... Read More

  Key responsibilities:Within the overall direction of the programme, the group, the remit of the project and in discussion with the Group Leader, you will make a significant input into determining the direction of the project within a three-year lifespan. To plan your own work and objectives on a 12-month basis and manage your experimental work within the project along with your supervisor.To work with limited supervision to identify, develop, modify and apply the necessary techniques to achieve the goals of the project.To introduce and apply new techniques across a wide range of disciplines and to have the creativity and initiative to develop novel approaches and methods where required.To ensure the research is carried out in accordance with good practice and in compliance with local policies and legal requirements.
  
  To contribute to the smooth running of the group, including the effective use of resources, training of others and taking responsibility for use of communal facilities.To enhance your research and generic skills through a tailored development programme. Working relationships: You will report to Drs Michel Goedert and Sjors Scheres and you will interact and collaborate with other Postdoctoral Scientists, Research Support staff and Students, not only in your group, but also across the LMB and with external groups as necessary.Additional information:This is a three-year training and development position for a Postdoctoral Scientist who has recently completed their doctoral studies, is moving into a new research discipline or has limited experience of key transferable skills. We support Postdoctoral Scientists with a range of formal and on-the-job training, including:
  • MRC training courses.
  • External training and personal development courses.
  • One-to-one training with your supervisor and other Scientists.You will commit to undertaking the following:
  • Developing and following a personal development plan.
  • Attending training courses.
  • Identifying additional training which will support you to develop your career. /*generated inline style */ Person Specification Academic qualifications: These should include a PhD in a relevant subject or due to complete a PhD within 6 months.Technical skills and expertise:Essential
  The successful candidate will have experience in the generation of experimental models of amyloid formation and/or cryo-EM/cryo-ET.Experience in standard molecular biology techniques of cloning and cell culture or protein purification.Desirable
  Experience in pluripotent stem cell conversion or cryo EM/cryo-ETTrack record of research:This will include contributions to published papers. Read Less

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