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Genomics England
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  • Job DescriptionAbout the Role   Are you passionate about nurturing inn... Read More
    Job Description

    About the Role   Are you passionate about nurturing innovation and empowering teams to solve complex, high impact technical problems? At Genomics England we are looking for two Principal Engineers to join the business in evolving and expanding the reach of genomics in the UK population.One of these roles will be working within our bio-pipelines service, where genomic data is processed to support critical clinical judgments. The Principal Engineer here will bring senior technical leadership to the modernisation of our bioinformatics workflows to support a growing number of strategic use-cases. The other will play a pivotal role in designing and delivering the technology to support a new population genomics programme. This programme will generate evidence and digital infrastructure to help make genomics a routine part of healthcare.As a Principal Engineer you will be a hands-on contributor with exemplary engineering skills, who can also think strategically to define architectural directions. You may have previously worked under a variety of different job titles within engineering and/or architecture, and you may have worked in a variety of organisational contexts. Whatever your past experience, it will have given you both technical breadth and depth.You will be a problem-solver who identifies risks, issues, gaps, and dependencies and takes ownership in bringing people together to find solutions. You will do this through your supportive, empathetic and collaborative behaviours, acting as coach, mentor, guide or constructive questioner as the situation demands. You are pragmatic but also mindful of the big picture, consciously balancing the immediate goals of teams against the long term direction for their products.About the Tech Stack Our existing infrastructure includes both on-premise High-Performance Compute clusters and AWS, and our bioinformatics workflows are orchestrated in Python / NextFlow. We leverage best-in-class tools like Dragen to do some of the heavy-lifting. We use things like Python, MongoDB and DynamoDB to deliver RESTful services that provide authoritative data for use during processing. We are working to become interoperable with the wider NHS via open standards like FHIR and GA4GH APIs. We have a standard tool chain which includes Terraform for infrastructure-as-code, GitLab for source code and CI/CD, Artifactory for software artefacts and DataDog for observability. Job Description Work alongside the service owner, architects, product managers, engineers, bioinformaticians and other subject matter experts to continuously evolve a roadmap for each programme. Be the voice of technical excellence in any conversation, ensuring that the functional, safety and operational characteristics of our products are continuously improving.  Stay abreast of emerging technologies, standards and industry trends and incorporate them into our software development practices.  Contribute to the wider conversation at Genomics England and help mature our technical practices. Essential Skills and Experience  Strong software engineering skills and awareness of software design patterns (Python is our preferred development language)  Knowledge of different database types and their applicability in different contexts (Postgres/Aurora, Elastic/OpenSearch and Apache Iceberg are in use at Genomics England) Experience shaping and guiding software architectural choices, both tactical as well as long-term architectural strategy and direction  Experience of API schema design and evolution  DevOps experience (CI/CD, Infrastructure as Code, operational monitoring and alerting)  Experience in at least one major public cloud (AWS preferred but not essential)  Strong interpersonal skills with a temperament that builds trust and connection within and across squads through open, honest communication  Experience mentoring & coaching junior colleagues to build high-performing teams Effective communication with non-technical team members and experience managing stakeholder relationships across team and organisational boundaries Comfortable engaging responsively with teams both remotely and in person when required  Ability to navigate rapidly to effective solutions through engaged and inclusive listening, clarity of thought, clear documentation, and succinct presentation  Desirable Experience  These skills are not essential but if you have any of them they may be an indicator that you would be well prepared to hit the ground running:  Background in healthcare or bioinformatics Experience in regulated environments  Experience integrating services with NHS/UK Government digital infrastructure Proficiency in handling large, complex data-sets using tools like Hadoop/EMR or Spark If you’re an experienced technologist who thrives on fostering collaboration to deliver positive outcomes, we’d love to hear from you. Join us at Genomics England and make a meaningful impact in the world of genomics.  
    Qualifications

    While we love to see and recognise the genuine value of relevant qualifications, we are primarily interested in your real-world experience. 

    Additional Information


    Salary From: £103,400 pa

    Closing Date: Monday 26th January @ 23:00 (UK time)Being an integral part of such a meaningful mission is extremely rewarding in itself, but in order to support our people, we’re continually improving our benefits package. We pride ourselves on investing in our people and supporting them to achieve their career goals, as well as offering a benefits package including: Generous Leave: 30 days’ holiday plus bank holidays, additional leave for long service, and the option to apply for up to 30 days of remote working abroad annually (approval required).Family-Friendly: Blended working arrangements, flexible working, enhanced maternity, paternity and shared parental leave benefits.Pension & Financial: Defined contribution pension (Genomics England double-matches up to 10%, however you can contribute more if you wish), Life Assurance (3x salary), and a Give As You Earn scheme.Learning & Development: Individual learning budgets, support for training and certifications, and reimbursement for one annual professional subscription (approval required).Recognition & Rewards: Employee recognition programme and referral scheme.Health & Wellbeing: Subsidised gym membership, a free Headspace account, and access to an Employee Assistance Programme, eye tests, flu jabs.Equal opportunities and our commitment to a diverse and inclusive workplace Genomics England is actively committed to providing and supporting an inclusive environment that promotes equity, diversity and inclusion best practice both within our community and in any other area where we have influence. We are proud of our diverse community where everyone can come to work and feel welcomed and treated with respect regardless of any disability, ethnicity, gender, gender identity, religion, sexual orientation, or social background. Genomics England’s policies of non-discrimination and equity and will be applied fairly to all people, regardless of age, disability, gender identity or reassignment, marital or civil partnership status, being pregnant or recently becoming a parent, race, religion or beliefs, sex or sexual orientation, length of service, whether full or part-time or employed under a permanent or a fixed-term contract or any other relevant factor.  Genomics England does not tolerate any form of discrimination, harassment, victimisation or bullying at work. Such behaviour undermines our mission and core values and diminishes the dignity, respect and integrity of all parties. Our People policies outline our commitment to inclusivity. We aim to remove barriers in our recruitment processes and to be flexible with our interview processes. Should you require any adjustments that may help you to fully participate in the recruitment process, we encourage you to discuss this with us.  CultureWe have four key behaviours that represent what we would like Genomics England to feel like and the culture we want to encourage, in order for us to achieve our mission. These behaviours help us all work well together, deliver on our outcomes, celebrate our successes and share feedback with each other. You can read about these and other aspects of our culture here Culture | Genomics England Blended working modelGenomics England operates a blended working model as we know our people appreciate the flexibility that hybrid working can bring. We expect most people to come into the office a minimum of 2 times each month. However, this will vary according to role and will be agreed with your team leader. There is no expectation that people will return to the office full time unless they want to, however, some of our roles require full time on site attendance e.g., lab teams, reception team. Our teams and squads have, and will continue to reflect on what works best for them to work together successfully and have the freedom to design working patterns to suit, beyond the minimum. Our office locations are: Canary Wharf, Cambridge and Leeds. Onboarding background checksAs part of our recruitment process, all successful candidates are subject to a Standard Disclosure and Barring Service (DBS) check.  We therefore require applicants to disclose any previous offences at point of application, as some unspent convictions may mean we are unable to proceed with your application due to the nature of our work in healthcare.  Read Less
  • Non-Executive Director (Finance)  

    Job DescriptionThe OpportunityWe are now looking for a candidate with... Read More
    Job Description

    The OpportunityWe are now looking for a candidate with significant financial & audit leadership expertise, ideally with experience at executive and non-executive level of audit committees. The successful candidate should demonstrate the capability to add value to our Board beyond the financial and audit expertise, bringing a track record of leadership within organisations and industries of comparable scale and complexity and able to play an important ambassadorial role for Genomics England both internally and externally.We already have an exceptional Board, with a wide range of experience and capabilities. Every member of the Board has a passionate interest in and responsibility for our work. This is a vital board role we are excited to encourage a leader of outstanding capability to join us. 
    Qualifications

    Please see the Candidate Brief above to learn of the essential and desirable criteria to be considered for this role. 

    Additional Information

    Appointment: This is a Ministerial appointment.Remuneration: this role attracts £7,883 per annum. It is non pensionable and payable via PAYE. Reasonable expenses are also payable in accordance with our Travel and Expenses Policy but expenses incurred in relation to travel to our London office are taxable.Term of appointment: Three years, renewable for a further term, and in exceptional circumstances renewal for a third term.Time commitment: the anticipated time commitment is a circa 15 to 20 days per annum. The role involves attendance at Board and the Audit Committee, providing advice as required, preparation time, travel and some work outside of meetings.Equal opportunities and our commitment to a diverse and inclusive workplace Genomics England is actively committed to providing and supporting an inclusive environment that promotes equity, diversity and inclusion best practice both within our community and in any other area where we have influence. We are proud of our diverse community where everyone can come to work and feel welcomed and treated with respect regardless of any disability, ethnicity, gender, gender identity, religion, sexual orientation, or social background. Genomics England’s policies of non-discrimination and equity and will be applied fairly to all people, regardless of age, disability, gender identity or reassignment, marital or civil partnership status, being pregnant or recently becoming a parent, race, religion or beliefs, sex or sexual orientation, length of service, whether full or part-time or employed under a permanent or a fixed-term contract or any other relevant factor.  Genomics England does not tolerate any form of discrimination, harassment, victimisation or bullying at work. Such behaviour undermines our mission and core values and diminishes the dignity, respect and integrity of all parties. Our People policies outline our commitment to inclusivity. We aim to remove barriers in our recruitment processes and to be flexible with our interview processes. Should you require any adjustments that may help you to fully participate in the recruitment process, we encourage you to discuss this with us.  CultureWe have four key behaviours that represent what we would like Genomics England to feel like and the culture we want to encourage, in order for us to achieve our mission. These behaviours help us all work well together, deliver on our outcomes, celebrate our successes and share feedback with each other. You can read about these and other aspects of our culture here Culture | Genomics England Read Less
  • Squad Coach - 12 Month FTC (we have office locations in Cambridge, Leeds & London)  

    - London
    Job DescriptionWe are looking for an experienced Squad Coach / Scrum M... Read More
    Job Description

    We are looking for an experienced Squad Coach / Scrum Master to join our thriving Agile practice.Here at Genomics England, Agility is core to achieving our company vision - to create a world where everyone benefits from personalised genomic medicine. We firmly believe Agile ways of working are key to:Enabling openness, transparency, retrospection and learningGenerating a culture of iteration and adaptabilityBuilding a sense of family, accountability and cohesionOur Squad Coaches are the cornerstone of Agility at Genomics England. They are essential to ensuring each squad strives towards exceptional levels of performance to deliver high-value, high-quality services that make a difference to the lives and treatment of patients in the UK living with cancer and rare diseases.You’ll work closely with cross-functional squads within the Newborns team, contributing to life-changing genomic services for the NHS and wider research communities.This role will suit a true collaborator and people person - someone who understands where they can add real value and is motivated by facilitating others to achieve great things.What you will be doing:Partner with Product, Tech, and Design Leads to ensure cohesive and outcome-focused squad leadershipSet up and continuously improve systems of work that promote transparency, flow, self-organisation, and alignment with the GEL Way and NHS/GDS standardsUse data and metrics (e.g. flow, squad health, OKRs) to guide continuous improvement and squad effectivenessApply systems thinking and root cause analysis to identify and remove systemic blockers to performanceCoach squads through tailored strategies that support their growth into high-performing, self-organising teamsFacilitate Agile ceremonies, OKR events, and workshops with purpose and engagementSupport the Product Manager with planning, visioning, and backlog management while keeping users at the centreProtect squads from distractions and help remove delivery impedimentsContribute to Agile capability building across GEL through training, pairing with fellow coaches, and evolving the GEL WayRole model inclusive, values-led leadership and help others navigate change with empathy and influence
    Qualifications

    Essential skills and experience for successRelevant experience in an Agile Coach / Scrum Master / Delivery Manager roleAbility to lead and organise 1-2 squads along with relevant stakeholders such as Product Manager, Technical Leads, Designers, Service Owners etc.Deep knowledge and experience with Agile ways of working frameworks like Scrum, KanbanDemonstrable experience of applying systems thinking, root cause analysis, etc. to identify and unpick tough and often systemic problems, proactively resolving these problemsOutcomes-oriented, data-driven, adaptive mindsetDemonstrable experience of using metrics to driver delivery excellenceExperience of coaching multidisciplinary digital teams to deliver digital services - from discovery, design, delivery, growth, continuous improvement to retirementExperience supporting teams to align around outcomes using OKRs or similar goal-setting frameworksGreat interpersonal and communication skills; an inspiring team player, coach, and leaderPassion for all things AgileGood understanding of the holistic Software Development Lifecycle and previous experience with DevOps practicesSolid working experience with the Atlassian toolkitDesirable skills and experience for successA recent Agile certification (just to show you love learning!)Knowledge of healthcare, life sciences or genomicsPrevious experience in a direct delivery roleKnowledge of frameworks that allow Agile methods to scaleExperience of matrix-managed organisationsExperience of Agile delivery in UK government, particularly the Government Digital Service (GDS) Service Standard

    Additional Information

    Please note: This is a 12-Month Fixed Term Contract (FTC).
    We have a blended working model, for this role you will be required on-site c. 8 days per month.

    Closing Date: Friday 9th January 2026Salary from: £60,000Being an integral part of such a meaningful mission is extremely rewarding in itself, but in order to support our people, we’re continually improving our benefits package. We pride ourselves on investing in our people and supporting them to achieve their career goals, as well as offering a benefits package including: Generous Leave: 30 days’ holiday plus bank holidays, additional leave for long service, and the option to apply for up to 30 days of remote working abroad annually (approval required).Family-Friendly: Blended working arrangements, flexible working, enhanced maternity, paternity and shared parental leave benefits.Pension & Financial: Defined contribution pension (Genomics England double-matches up to 10%, however you can contribute more if you wish), Life Assurance (3x salary), and a Give As You Earn scheme.Learning & Development: Individual learning budgets, support for training and certifications, and reimbursement for one annual professional subscription (approval required).Recognition & Rewards: Employee recognition programme and referral scheme.Health & Wellbeing: Subsidised gym membership, a free Headspace account, and access to an Employee Assistance Programme, eye tests, flu jabs.Equal opportunities and our commitment to a diverse and inclusive workplace Genomics England is actively committed to providing and supporting an inclusive environment that promotes equity, diversity and inclusion best practice both within our community and in any other area where we have influence. We are proud of our diverse community where everyone can come to work and feel welcomed and treated with respect regardless of any disability, ethnicity, gender, gender identity, religion, sexual orientation, or social background. Genomics England’s policies of non-discrimination and equity and will be applied fairly to all people, regardless of age, disability, gender identity or reassignment, marital or civil partnership status, being pregnant or recently becoming a parent, race, religion or beliefs, sex or sexual orientation, length of service, whether full or part-time or employed under a permanent or a fixed-term contract or any other relevant factor.  Genomics England does not tolerate any form of discrimination, harassment, victimisation or bullying at work. Such behaviour undermines our mission and core values and diminishes the dignity, respect and integrity of all parties. Our People policies outline our commitment to inclusivity. We aim to remove barriers in our recruitment processes and to be flexible with our interview processes. Should you require any adjustments that may help you to fully participate in the recruitment process, we encourage you to discuss this with us.  CultureWe have four key behaviours that represent what we would like Genomics England to feel like and the culture we want to encourage, in order for us to achieve our mission. These behaviours help us all work well together, deliver on our outcomes, celebrate our successes and share feedback with each other. You can read about these and other aspects of our culture here Culture | Genomics England Blended working modelGenomics England operates a blended working model as we know our people appreciate the flexibility that hybrid working can bring. We expect most people to come into the office a minimum of 2 times each month. However, this will vary according to role and will be agreed with your team leader. There is no expectation that people will return to the office full time unless they want to, however, some of our roles require full time on site attendance e.g., lab teams, reception team. Our teams and squads have, and will continue to reflect on what works best for them to work together successfully and have the freedom to design working patterns to suit, beyond the minimum. Our office locations are: Canary Wharf, Cambridge and Leeds. Onboarding background checksAs part of our recruitment process, all successful candidates are subject to a Standard Disclosure and Barring Service (DBS) check.  We therefore require applicants to disclose any previous offences at point of application, as some unspent convictions may mean we are unable to proceed with your application due to the nature of our work in healthcare.  Read Less
  • Senior Service Designer (we have office locations in Cambridge, Leeds and London)  

    - London
    Job DescriptionWe are hiring a Senior Service Designer to play a pivot... Read More
    Job Description

    We are hiring a Senior Service Designer to play a pivotal role in shaping how our services are experienced and delivered.  This role involves mapping the end-to-end service, including people, processes, data, and platforms to provide the Service Owner and Head of Research Cohorts with actionable insights, while working closely with them to design and enhance the service experience.” You will lead the creation of service journeys by translating user needs and service goals into human centred solutions across delivery teams. The role involves organising your own work cadence with the Service Owner and stakeholders, engaging regularly to understand challenges, capture needs, and stay aligned.  It also requires visualising and communicating complex problem spaces, using sketches and prototypes to guide decision making, while collaborating closely with stakeholders, principal designers, researchers, and broader design teams to build the assets that bring future states to life. Everyday responsibilities include: Solve medium-to-high complexity service design challenges with a principled, human-centred approach. Translate insights, user stories, and requirements into design solutions, ensuring user needs are met across the service, including back stages. Deliver clear design outputs, such as user journeys, service maps, design briefs, and EPICs to enable decision-making and implementation. Scope work effectively and plan design activities using an iterative, agile approach. Collaborate efficiently with product and service delivery teams to ensure connected, implementable service experiences across key touchpoints. Facilitate decision-making and co-creation across multiple teams using appropriate methods. Advocate for users, influencing teams to build equitable, inclusive services that meet user needs effectively. Participate in design research and testing, incorporating learnings to continuously improve services and inform team plans and roadmaps. Skills and experience for success:Proven expertise in service design, with hands-on experience using tools such as service blueprints, journey maps, service patterns, and process mapping, and a strong portfolio demonstrating human-centred design in complex services.Skilled at leading cross-functional work, bringing together colleagues across disciplines, including scientists, technical specialists, and delivery teams to collaborate effectively and deliver shared outcomes. Strong strategic and systems thinking, able to tackle complex service challenges across front-end, back-end, and behind the scenes processes, while navigating governance, policy, and regulatory constraints. Comfortable working with complex data flows, technical disciplines, and ambiguous problems, translating insights into actionable design solutions that support decision-making. Excellent communication and problem-solving skills, with the ability to visualise and articulate complex problems, facilitate co-creation, and lead projects with a human-centred approach. 
    Qualifications

    While your qualifications are certainly important and provide a foundation, we are particularly interested in understanding the breadth and depth of your overall experience, as this gives us a clearer picture of what you can bring to the role.

    Additional Information

    Salary from: £66,500Please provide a cover letter explaining how your skills and experience align with this role and its requirements. Closing date for applications – Monday 12th January 2026 Being an integral part of such a meaningful mission is extremely rewarding in itself, but in order to support our people, we’re continually improving our benefits package. We pride ourselves on investing in our people and supporting them to achieve their career goals, as well as offering a benefits package including: Generous Leave: 30 days’ holiday plus bank holidays, additional leave for long service, and the option to apply for up to 30 days of remote working abroad annually (approval required).Family-Friendly: Blended working arrangements, flexible working, enhanced maternity, paternity and shared parental leave benefits.Pension & Financial: Defined contribution pension (Genomics England double-matches up to 10%, however you can contribute more if you wish), Life Assurance (3x salary), and a Give As You Earn scheme.Learning & Development: Individual learning budgets, support for training and certifications, and reimbursement for one annual professional subscription (approval required).Recognition & Rewards: Employee recognition programme and referral scheme.Health & Wellbeing: Subsidised gym membership, a free Headspace account, and access to an Employee Assistance Programme, eye tests, flu jabs.Equal opportunities and our commitment to a diverse and inclusive workplace Genomics England is actively committed to providing and supporting an inclusive environment that promotes equity, diversity and inclusion best practice both within our community and in any other area where we have influence. We are proud of our diverse community where everyone can come to work and feel welcomed and treated with respect regardless of any disability, ethnicity, gender, gender identity, religion, sexual orientation, or social background. Genomics England’s policies of non-discrimination and equity and will be applied fairly to all people, regardless of age, disability, gender identity or reassignment, marital or civil partnership status, being pregnant or recently becoming a parent, race, religion or beliefs, sex or sexual orientation, length of service, whether full or part-time or employed under a permanent or a fixed-term contract or any other relevant factor.  Genomics England does not tolerate any form of discrimination, harassment, victimisation or bullying at work. Such behaviour undermines our mission and core values and diminishes the dignity, respect and integrity of all parties. Our People policies outline our commitment to inclusivity. We aim to remove barriers in our recruitment processes and to be flexible with our interview processes. Should you require any adjustments that may help you to fully participate in the recruitment process, we encourage you to discuss this with us.  CultureWe have four key behaviours that represent what we would like Genomics England to feel like and the culture we want to encourage, in order for us to achieve our mission. These behaviours help us all work well together, deliver on our outcomes, celebrate our successes and share feedback with each other. You can read about these and other aspects of our culture here Culture | Genomics England Blended working modelGenomics England operates a blended working model as we know our people appreciate the flexibility that hybrid working can bring. We expect most people to come into the office a minimum of 2 times each month. However, this will vary according to role and will be agreed with your team leader. There is no expectation that people will return to the office full time unless they want to, however, some of our roles require full time on site attendance e.g., lab teams, reception team. Our teams and squads have, and will continue to reflect on what works best for them to work together successfully and have the freedom to design working patterns to suit, beyond the minimum. Our office locations are: Canary Wharf, Cambridge and Leeds. Onboarding background checksAs part of our recruitment process, all successful candidates are subject to a Standard Disclosure and Barring Service (DBS) check.  We therefore require applicants to disclose any previous offences at point of application, as some unspent convictions may mean we are unable to proceed with your application due to the nature of our work in healthcare.  Read Less

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