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AstraZeneca
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  • Senior Director, CVRM Genomics Therapeutic Area Lead  

    - Cambridge
    Make a meaningful impact on patients’ lives around the worldAstraZenec... Read More
    Make a meaningful impact on patients’ lives around the worldAstraZeneca’s mission is to push the boundaries of science to deliver life-changing medicines. The Centre for Genomics Research (CGR) is advancing one of the world’s most ambitious efforts to apply human genomics and population-scale health data to reshape how diseases are understood and how therapeutic decisions are made. Our work enables clinically meaningful, genetically informed decision-making across the full drug development pipeline.A unique leadership opportunity to bridge science and clinical care.We are seeking a leader with an MD and/or PhD in a relevant biomedical field who sees population genomics as a tool for understanding disease biology, guiding therapeutic development, and improving patient outcomes.In this role, you will shape how human genetic and multi-omic evidence informs AstraZeneca’s strategy and pipeline in Cardiovascular, Renal, and Metabolic (CVRM) diseases. You will play a central role in determining how we select targets, design trials, stratify patients, understand drug response variation, and ultimately bring therapies to the patients who will benefit most.You will also contribute directly to AstraZeneca’s global scientific footprint, working across a 60+ partner international network including leading academic medical centers, biobanks, and industry consortia.You will report directly to the Vice President, Head of the Centre for Genomics Research, and serve as a member of the CGR Leadership Team.As the CVRM Genomics Therapeutic Area Lead, you will:Define and lead the CVRM Genomic strategy for CGR, ensuring strong alignment to unmet patient needs and AstraZeneca’s therapeutic area priorities.Bring clinical reasoning and genetic insight together to identify disease mechanisms, prioritize therapeutic targets, and develop biomarker and patient identification strategies.Integrate genomic, multi-omic, clinical, biomarker, and real-world evidence data to evaluate disease heterogeneity and causal mechanistic pathways, support mechanism-based development and indication expansion, and inform lifecycle management and post-market investigation.Collaborate with CVRM TA leadership to apply population genomic insight to inform patient selection and disease subtyping, identify clinical biomarkers and biomarker-driven stratification approaches that enhance clinical trial interpretability and raise the likelihood of therapeutic success.Lead scientific collaboration across AstraZeneca and the global research community, leveraging clinical insight to prioritize high-value partnerships and investments.Mentor and inspire cross-functional teams of scientists, clinicians, geneticists, and data scientists toward shared goals.Essential CriteriaMD (or international equivalent) and/or relevant PhD with deep understanding of CVRM disease biology, gained through clinical practice, translational research, or therapeutic development.Significant experience in clinical research and/or drug development in pharmaceutical or academic environmentsDemonstrated ability to apply human genetics or multi-omics to inform disease mechanisms, patient stratification, therapeutic hypotheses, or clinical trial strategy.Experience in genetic epidemiology and/or rare variant interpretation, including evaluating variant pathogenicity, penetrance, and clinical relevance in patient populations.Proven track record leading complex, cross-functional scientific or clinical research across matrixed teams and external partners (, academic, biotech, consortia).Collaborative, patient-centered leader who thrives working across disciplines to solve translational challenges and shape how medicine is developed and used at scaleExperience contributing to clinical trial design, patient enrichment strategies, or biomarker-driven study planning.Excellent communicator able to convey clinical reasoning and genomic insights to audiences ranging from data scientists to therapy area leadership and governance boards.Ability to influence portfolio and investment decisions through scientific and clinical reasoning.Experience mentoring and developing scientific talentDesirable CriteriaRecognized scientific contributions (publications, conference presentations, guideline contributions, etc.).Experience leveraging human genomics to inform clinical development, biomarker strategy, or real-world evidence studies.Familiarity with regulatory, ethical, or privacy considerations for genomic research.Clinical experienceAt AstraZeneca, we’re dedicated to being a Great Place to Work, where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference in medicine, patients and society. An inclusive culture that champions diversity and collaboration, we are committed to lifelong learning, growth and development.Date Posted11-Mar-2026Closing Date17-Mar-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Associate Director, Data Services & AI - Evinova  

    - London
    Associate Director, Data Services & AI - EvinovaLocation: St Pancras L... Read More
    Associate Director, Data Services & AI - EvinovaLocation: St Pancras LondonSalary: Competitive + Excellent BenefitsAbout EvinovaEvinova, a fully owned subsidiary of AstraZeneca, is a pioneering health tech business with a mission to transform billions of patients’ lives through technology, data, and innovative delivery practices. We deliver globally-scaled digital health solutions that are science-based, evidence-led, and human experience-driven—serving clinical trial sponsors, research organizations, care teams, and patients across 40+ countries.Our platform accelerates clinical development, elevates patient experiences, and enables better health outcomes. By joining Evinova, you’ll be part of a diverse, ambitious team that pushes the boundaries of science by digitally empowering a deeper understanding of the patients we serve. We believe that when unexpected teams come together, bold thinking is unleashed, inspiring life-changing medicines and digital solutions.Role OverviewWe are seeking an accomplished Associate Director, Data Services + AI to lead, grow, and evolve our Data Services function. This is a player-coach leadership role: you will guide and develop a high-performing team of Clinical Data Analysts while also remaining hands-on with customer data delivery, complex problem-solving, and strategic initiatives.You will own the end-to-end data service lifecycle across active studies - from setup and ingestion through maintenance, troubleshooting, and study close-out (database lock, final data delivery, archiving, and compliance readiness).A core responsibility for this role is driving the evolution of AI tools that enhance efficiency, consistency, and quality across the data delivery lifecycle. You will collaborate closely with Product, Engineering, Clinical teams, and Customers to shape automation opportunities and embed scalable, intelligent workflows into our operational foundation. You’ll help define how AI is applied across our data ecosystem, ensuring that new capabilities are purposeful, intuitive, and aligned with real operational needs. You will also play a key role in refining these solutions as they mature, helping the organization adopt and benefit from them effectively.ResponsibilitiesTeam Leadership & DevelopmentLead, mentor, and develop a team of Clinical Data Analysts and Data Delivery specialists; cultivate a culture of ownership, quality, and continuous improvement.Act as the escalation point for complex data delivery issues, providing hands-on guidance and strategic direction.Shape resource planning, role definitions, onboarding, and capability building as the Data Services function grows.Data Delivery OwnershipOversee and contribute to the development, review, and approval of Data Management Plans, Data Transfer Agreements, and study-specific documentation.Ensure smooth configuration and validation of data pipelines, mapping specifications, and test datasets.Drive consistency and quality across data transformation processes, clinical data standards, and digital measurement endpoints (, eCOA, sensors, wearables).Manage issue resolution and cross-functional problem-solving during study execution, minimizing operational impact.Lead and manage the full study close‑out process, including database lock, audit‑readiness activities, and coordination of all regulatory‑required steps.Oversee the preparation, validation, and archiving of final study data, along with associated logs, configurations, and decision history to ensure compliance and traceability.AI & Automation – Tools + Process InnovationIdentify and prioritize opportunities to automate data delivery workflows using AI/ML, rule engines, and procedural automation.Partner with Product and Engineering teams to design, prototype, and launch internal tools that reduce manual effort, improve accuracy, and scale operations.Establish a roadmap for automation across data ingestion, validation, quality checks, reporting, and close-out.Promote a culture of automation-first thinking within the Data Services team.Cross-Functional Collaboration & Continuous ImprovementRepresent the Data Services function in customer meetings, internal governance forums, and cross-functional delivery discussions.Partner with Product & Engineering to influence platform enhancements based on real-world data delivery needs.Drive process standardization, documentation, and operational maturity across the end-to-end data delivery lifecycle.Champion metrics, KPIs, and feedback loops to improve efficiency, quality, and predictability.Essential RequirementsBachelor’s or Master’s degree in a relevant field (, Clinical Data Management, Computer Science, Data Engineering).Demonstrated success in leading data teams in a “player-coach” capacity.Strong understanding of clinical data standards, transformation pipelines, digital measurement endpoints, and regulatory frameworks (GxP, ICH GCP, GDPR, FDA 21 CFR).Experience with JSON/TypeScript data mapping, GitHub workflows, scripting, and data validation frameworks.Familiarity with cloud-based environments (, AWS S3), workflow tools (JIRA), and coding environments (VSCode).Experience with SAS Universal Viewer (SAS7BDAT) or similar clinical data tools.Prior involvement in database lock, data reconciliation, or study close-out activities.Excellent communication and collaboration skills across technical and clinical teams.Preferred Requirements Experience building or deploying AI/ML-based tools, automation workflows, or data quality engines.Exposure to clinical technology products or digital health platforms at scale.Ability to translate operational pain points into structured requirements for Product & Engineering.Why Join Evinova?At Evinova, you’ll help deliver digital health solutions that accelerate clinical development, reduce patient burden, and improve outcomes for sponsors, sites, and patients. You’ll be part of a team that values:Science-led innovation: We follow the science and push boundaries with evidence-led solutions.Patient-first mindset: Every decision is made with the patient in mind.Collaboration and empowerment: We believe in the power of diverse teams and encourage bold thinking.Integrity and transparency: We act with accountability and prioritize doing the right thing.Entrepreneurial spirit: We drive sustainable change and take smart risks.We balance the expectation of in-person collaboration (minimum three days per week in the office / 60% overall) with individual flexibility, respecting the need for work-life balance.Ready to Make a Difference?Join Evinova and AstraZeneca in our mission to transform clinical research and deliver life-changing medicines. Be part of a unique and ambitious world - where courage, curiosity, and collaboration drive breakthroughs for patients everywhere.Apply now and help us shape the future of digital health!Where can I find out more? Learn more about Evinova: Follow Evinova on LinkedIn: Date Posted09-Mar-2026Closing Date13-Mar-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Job Title: Scientist, Protein Sciences& Analytics, Biologics Engineeri... Read More
    Job Title: Scientist, Protein Sciences& Analytics, Biologics Engineering Location: Cambridge, UKSalary: Competitive with excellent benefits Introduction to the Role:Early-stage biologics developability is essential foridentifyingmolecular liabilities before candidates enter intensive downstream development. By applyinghighthroughputbiophysical assays and in silico approaches,developability scientists generate rich datasets that reveal how sequence and structural features influence molecular behaviour. These experimentally grounded insights not only guide engineering decisions but also serve ashighqualitytraining data for generative machine learning models, enabling the predictive design of more stable, manufacturable biologic therapeutics from the beginning.Biologics Engineering Functionin the UKis basedat our newstate-of-the-artDiscovery Centre (DISC)locatedon the Cambridge Biomedical Campus.Biologics Engineeringis responsible forthe discovery and optimisation of biological candidate drugs to support alltherapy area drug discovery pipelines and for the development of in-house biologics discovery platforms and novel drug modalities to support future drug discovery efforts. About the Role:We areseekinga highly skilled and motivated Scientist to support our biologics discovery pipeline by generating and interpretinghighqualitydevelopability data. The role involves providingexperimentalsupporttothehigh-throughputdevelopabilityplatformsto characteriseon adiversebiologicmodalities. TechniquesincludeBLI (BioLayerInterferometry), ELISAs (EnzymeLinkedImmunosorbent Assays), DSF (Differential Scanning Fluorimetry), DLS (Dynamic Light Scattering), and automation workflows. The successful candidate will join the Analytics and Developability Team in Cambridge and willbe responsible forexecuting experiments; developing and validating assays; implementing automation solutions; and performing complex correlative data analyses to generate actionable insights. This primarilylab basedrole requires close collaboration within a multidisciplinary team focused on biologics production and characterization, working closely with partners across therapy areas and Data Science & Artificial Intelligence.Key ResponsibilitiesExecute experiments using BLI (Octet) and ELISAsto evaluate/screen biologics for non-specific bindingand self-association.Execute experiments for stability and particle characterization of biologics using the Prometheus Panta (DSF andDLS)orsimilarinstruments.Ability towork withdifferentautomation solutions to streamline experimental workflows and increase efficiency.Analyzeand interpret experimental data, including performing complex correlative analyses linking biophysical parameters to PK properties across diverse biologic modalities, and present findings tocrossfunctionalteamsCollaborate with multidisciplinary teams to support drug discovery projects by providingexpertisein protein-protein interactions.Stay abreast of the latest scientific and technological advancements in the field ofdevelopabilityand contribute to the implementation of new techniques and methodologies.Essential Requirements BSc/MScdegreeand/orwith equivalent lab-based experience.Hands-on experiencewith Octet andhigh-throughputELISAassaysto evaluate/screen biologics for non-specific bindingand self-association.Hands-on experience designing anddeterminingstability measurements byDSF/DLSplatforms(preferably withhand-on experienceonthePrometheus Pantaor equivalent instrument).Demonstratedhandsonexperience developing and operating automation workflows, including the integration of biochemical/biophysical assay formats intohighthroughputplatforms.Experience performing statistical analyses.Excellent understanding ofdifferentPost-translationalmodifications (PTMs)and impact onbiologicsdevelopability.Ability to provide solutions to a variety of complex problems , ability to dissectcomplexbiophysical properties.Ability tooptimizeprotocols, troubleshoot, interpret experimental results/data, andmaintainaccurate, high quality and up-to-date experimental records.Excellent communication and collaboration skills, with the ability to work effectively in a multidisciplinary team environment and with an ability to quickly learn and embracenew technologies.Desirable Requirements Experiencewithinsilicoprotein structureanalysistools (AlphaFold,RoseTTAFoldetc.)Experience with other biophysical characterisation techniques, such asSPRandmass spectrometry.Experience with molecular biology, proteinpurificationand cell culture techniques.Experience working in a high-throughput environment, as well as using high-throughput automation and liquid-handling systems , HamiltonRobotics liquid handlers.Abackground inbiologicsdrug discovery and development in the pharmaceutical industry.Experience with Signals ELN andGenedataBiologics platforms.Why AstraZeneca:AstraZeneca is a science-led, global biopharmaceutical company, with a focused portfolio in core therapies. At AstraZeneca we turn ideas into life changing medicines. We are committed to improving the health and lives of people across the globe, through our research and development platform, and a growing late-stage pipeline. Working in over 100 countries, we have strength in emerging markets, and our medicines are used by millions of patients and clinicians worldwide. Working here means being results-oriented and working together to make the impossible a reality.
    Here you will apply cutting-edge biophysics, automation, and AI-enabled analytics to help transform the future of cancer treatment. We unite decisive, science-driven teams who act fast on smart risks, speak up, and challenge convention—always guided by evidence. With a deep pipeline and unparalleled data, you will collaborate with diverse experts, learn across disciplines, and see your work directly influence how new medicines move forward. We value kindness alongside ambition, and we bring unexpected teams together to unleash bold thinking that turns complex problems into meaningful progress for patients.Where can I find out more? Our Social Media,Follow AstraZeneca on LinkedIn Follow AstraZeneca on Facebook Follow AstraZeneca on Instagram
     If you’re ready to turn high-throughput developability data into better biologics with real patient impact, step into this Cambridge role and show us how you will elevate our science and speed our decisions!Date Posted06-Mar-2026Closing Date17-Mar-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Director Enterprise Architecture  

    - Macclesfield
    Introduction to role:Are you ready to develop an enterprise architectu... Read More
    Introduction to role:Are you ready to develop an enterprise architecture that strengthens product quality and speeds up the provision of medications to patients worldwide? In this role, you will lead the end-to-end architecture across Pharmaceutical Technology, Quality Control, and Global Quality Assurance—linking datasets, artificial intelligence and machine learning solutions, applications, and platforms to clear business outcomes in a highly regulated environment.From day one, you will develop a vision for architecture spanning one to five years and bring coherence to a sophisticated global portfolio. Can you see yourself simplifying and standardizing how we assure product quality across sites, minimizing exposure and expenses while growing agility? You will create the foundations that enable faster, safer decisions from lab to plant to release.You will join an experienced architecture community that moves quickly, challenges how work gets done, and unites teams with varied strengths behind pragmatic standards. Your judgment will guide strategic choices, your governance will unlock value at pace, and your leadership will build the capabilities that keep our technology ecosystem resilient and ready for what’s next.Accountabilities:Provide coordinated compose mentorship throughout Business, data science, intelligent systems, application development, and technological areas related to pharmaceutical tech, quality checking, and international quality assurance, ensuring solutions deliver measurable capability uplift.Architecture Strategy and Roadmaps: Define and own the develop principles, protocols, and roadmaps covering a timeframe spanning from one to as many as five years. Align them with corporate targets and regulatory needs. Set the North Star and sequence investments that improve value.Strategic Decision Authority: Act as the authority for major architecture decisions; approve solution builds, guide segment architectures, and ensure builds balance speed, risk, and cost.Portfolio Simplification and Risk Reduction: Continuously align capabilities to current objectives; rationalize and simplify to reduce technical risk and TCO while improving resilience and accuracy of data.Governance and Cross-Functional Engagement: Participate in steering teams, design authorities, and standards forums; bring clarity to trade-offs and ensure disciplined, outcome-focused decision-making.Trend Sensing and Thought Leadership: Examine sector and business environment developments relevant to your domain; translate insights into actionable mentorship and investments that keep us ahead.Standards, Procedures, and Tools: Coordinate the building and adoption of EA guidelines, workflows, and instruments; embed compliance validation and reliable data practices as a fundamental element.External Partnerships and Product Evaluation: Establish strategic collaborations with major providers and integration specialists; evaluate products, develop cases, and secure value through informed choices.Lead 5 to 8 architects and a wider matrix community. Mentor, manage performance, develop expertise, and build communities of practice to increase impact.Work globally across sites and functions. Partner with research and development, production, technical operations, and distribution teams. Ensure delivery of consistent, high-quality architectures across complex, large-scale environments.Essential Skills/Experience:Proven experience providing enterprise design leadership across Business, Data, AI/ML, Application, and Technology within Pharmaceutical Technology, QC, and Global QA.Demonstrated ability to define architecture strategy, standards, and 1–5 year roadmaps aligned to business priorities and supervised operating requirements.Authority to make and govern strategic architecture decisions; experience signing off solution blueprints and guiding segment architectures.Track record of continuously aligning capabilities with business objectives, rationalizing and simplifying portfolios to reduce risk and cost.Active participation in cross-functional decision-making bodies (, project steering teams, technical design authorities) and design/standards governance forums.Evidence of championing enterprise architecture initiatives across technology organizations; ability to analyse market and industry trends and assess impact.Leadership of EA standards, processes, and tooling, with embedded GxP validation and measures ensuring data reliability in architectures.Experience establishing partnerships with key technology suppliers and system integrators; evaluating products and shaping business cases.Dedication to capability development through mentoring, collaborative learning groups, and standards ownership.People leadership of 5–8 architects with varied seniority, plus matrix leadership across adjacent domains and programs; accountable for coaching, performance management, capability building, and delegation.Success operating with a global remit across multiple countries and functions, with interfaces to R&D, Manufacturing/Tech Ops, and Supply Chain.Desirable Skills/Experience:Certification or formal training in enterprise architecture frameworks (, TOGAF) and experience with modern EA tooling (, LeanIX, Ardoq).Deep familiarity with GxP, 21 CFR Part 11, Annex 11, and data integrity principles, including experience navigating audits and validations.Hands-on leadership of cloud-centric architectures (Azure/AWS), data platforms, and AI/ML enablement in QC/QA contexts.Knowledge of quality and manufacturing ecosystems such as QMS, LIMS, MES, serialization, and release/lot disposition processes.Proven outcomes in portfolio simplification, cost reduction, and risk mitigation at enterprise scale.Strong vendor management and negotiation skills; ability to structure value-focused contracts and partnerships.Executive communication and storytelling skills that influence senior stakeholders and align diverse teams.Advanced degree in a relevant field or equivalent experience driving transformation in complex, regulated environments.Why AstraZeneca:Here, architecture is a catalyst for business performance and patient impact. You will work where unexpected teams sit in the same room to unlock bold thinking, uniting science, operations, and technology to create simpler, faster, safer ways of working. We match ambition with support: clear purpose, access to cutting-edge tools, and a collaborative culture that values kindness alongside challenge. Your designs won’t gather dust—they will be adopted, scaled globally, and felt in how quickly and reliably we deliver life-changing medicines.Call to Action:If you are ready to set the architectural direction that elevates quality, reduces risk, and accelerates medicines to patients at global scale, seize this opportunity to lead, simplify, and deliver impact now!Date Posted03-Mar-2026Closing Date12-Mar-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Study Contract Manager  

    - Luton
    Introduction to role:Are you ready to turn precise contracting into fa... Read More
    Introduction to role:
    Are you ready to turn precise contracting into faster site start-up and greater impact for people living with cancer? Do you thrive at the intersection of finance, law, and clinical operations, where clear agreements drive real-world outcomes?In this role, you will shape how clinical sites partner with us, ensuring budgets reflect Fair Market Value, terms are watertight, and timelines move with purpose. Your work will help accelerate studies across a rich pipeline in cancer, connecting rigorous contracting with patient access to novel therapies sooner.You will join a high-energy team committed to advancing transformative medicines. By leading negotiations and safeguarding contract integrity, you will remove friction from study start-up, protect audit readiness, and enable our scientists and clinicians to focus on delivering the next wave of breakthroughs.Accountabilities:Local Contracting Excellence: Adapt global agreement templates for local use in line with local requirements and SOPs to ensure compliant, fit-for-purpose contracts.Budget Development: Build clinical site budgets based on Fair Market Value to create transparent and sustainable financial frameworks for each site.Site Negotiations: Negotiate agreement language and budgets with clinical study sites to align expectations, mitigate risk, and set studies up for success.Legal Interface: Serve as a point of contact with Legal, when needed, to uphold the integrity of contracts and resolve issues efficiently.End-to-End Contract Ownership: Maintain the status of each agreement, budgets, issues, payments, amendments, and all related communications throughout the study lifecycle.Document Integrity: Ensure final contract documents accurately reflect negotiated agreements and are complete, consistent, and ready for execution.Start-Up Acceleration: Drive timely execution of all agreements to meet or beat site start-up timelines and keep studies on plan.Audit Readiness: Support internal and external audit activities, ensuring documentation and processes meet expectations at any time.Compliance Stewardship: Uphold our Code of Conduct and all policies relating to people, finance, technology, and security.Trial Master File Discipline: Ensure all contracts are accurately filed in the Trial Master File to enable transparency and inspection readiness.Essential Skills/Experience:Adapt global templates of agreements to local use in accordance with local requirements and SOPs.Develop and negotiate clinical site budgets based on Fair Market Value.Negotiate agreement language and budget with clinical study sites.Act as point of contact and interface with Legal if necessary to ensure integrity of contracts.For each agreement maintain the status of agreement, budgets, issues, payments, any amendments for the duration of the study, and communications with internal and external sources.Ensure final contract documents are consistent with agreements reached at negotiations.Ensure all agreements are executed in a timely manner contributing to efficient site start-up timelines.Support internal and external audit activities.Ensure compliance with AstraZeneca’s Code of Conduct and company policies and procedures relating to people, finance, technology and security.Ensure that all contracts are included in the TMF.Desirable Skills/Experience:Training and mentoring of new members of the local Study Team regarding financial/contractual issues and sharing experiences.Support preparation and negotiation of a Local Master Service Agreement.Contribute to process improvements, knowledge transfer and best practice sharing.Why AstraZeneca:
    Here, your contracting expertise fuels science with urgency and care. We are advancing a diverse pipeline in cancer and investing at pace, aiming to bring multiple new medicines to patients by 2025. You will work alongside experts from clinical operations, legal, finance, data, and discovery—unexpected teams in the same room unleashing bold thinking—so that complex studies move faster and smarter. We back ambition with practical support, value kindness alongside high standards, and collaborate deeply with leading hospitals and academic centers to tackle some of the toughest cancers. Every precise clause you negotiate and every day you save helps transform potential into real patient benefit.Call to Action:
    If you are ready to turn sharp negotiation and meticulous execution into faster trials and bigger patient impact, step forward and help shape what comes next!Date Posted03-mar.-2026Closing Date17-mar.-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Business Planning & Process Manager  

    - London
    Business Planning & Process ManagerLocation: London, UKCompetitive Sal... Read More
    Business Planning & Process ManagerLocation: London, UK
    Competitive Salary & Excellent Company BenefitsThe Oncology Business Unit is seeking an exceptional Business Planning & Process Manager to drive strategic and commercially focused initiatives that enhance franchise performance and execution excellence. This role goes beyond traditional PMO activity — requiring hands‑on commercial experience, strong organisational skills, and the ability to partner closely with customer‑facing and cross‑functional teams to uplift the quality and consistency of core commercial processes.Operating at the heart of the Oncology Business Unit, you will work with senior stakeholders — including the Business Operations Lead, OBEX Director, Strategy & Operations Lead, Brand Leads and Franchise Heads — to uplift capabilities across customer engagement, strategic and operational planning, and launch preparedness. You will ensure our ways of working are robust, insight‑driven, strategically aligned, and continually improving.By embedding best‑practice commercial processes, harmonising planning approaches, and enabling clear, consistent execution across brands and franchises, you will help AstraZeneca Oncology continue to lead the UK market.Key Responsibilities (Strategic)Drive strategic project delivery aligned with the Oncology Business Unit’s transformation priorities, ensuring initiatives enhance franchise performance and support future growth.Strengthen core commercial processes (, planning cycles, customer engagement workflows, launch readiness frameworks), ensuring they are consistent, efficient and insight‑driven.Partner with franchise and functional leaders to clarify strategic priorities and shape planning and execution frameworks that support high‑quality commercial decision‑making.Champion continuous improvement, identifying opportunities to simplify or uplift processes and helping embed improved ways of working.Leverage above‑market insights, working with global and EUCAN teams to bring relevant tools, frameworks and best practices into local execution.Key Responsibilities (Operational)Coordinate and integrate high priority‑ OBU initiatives within a structured business calendar, ensuring clear sequencing and strong execution.Monitor project progress and implementation, identifying risks early, escalating where needed, and ensuring appropriate corrective actions are taken.Provide clear, timely and actionable communication to leadership and cross functional teams to support alignment and informed ‑decision making‑.Ensure clarity of responsibilities, timelines and deliverables, helping teams maintain momentum and stay focused on business-critical‑ activity.Support teams in adopting improved processes, ensuring governance standards are met and enabling smooth implementation of new or refined ways of working.Maintain compliance with internal governance and external regulatory requirements related to UK oncology operations.Essential Requirements:Commercial Experience: Hands-on experience in a commercial role within pharmaceuticals or a similar regulated industry (, brand management, field sales management, marketing, commercial excellence‑ or business operations).Strong Business Acumen: Understanding of core commercial drivers such as customer engagement, brand planning, launch readiness, and franchise performance levers.Process & Planning Skills: Experience contributing to or improving commercial planning cycles, operational planning, or execution frameworks.Cross Functional‑ Collaboration: Proven ability to work effectively with marketing, sales, medical, access and operations teams, aligning on shared priorities and deliverables.Execution Focus: Ability to take ownership of workstreams, keep activity on track, and ensure outputs are high quality, ‑insight informed‑ and commercially relevant.Communication & Influence: Strong communicator able to distil information clearly and influence stakeholders constructively without formal authority.Continuous Improvement Mindset: Demonstrated interest in improving how teams work, simplifying processes, and embedding best practice in day-to-day‑ operations.Desirable RequirementsExperience supporting brand or launch excellence activities (, cross functional‑ planning, customer engagement improvement, insights integration).Exposure to improving commercial processes such as planning governance, capability uplift, customer engagement workflows, or execution standards.Familiarity with the UK oncology landscape or specialist medicines.Experience working with global or regional teams to localise frameworks or processes.Confidence working with data and insights to inform recommendations or process improvements.Interested? Apply by submitting your CV by COB 12 March 2026.Date Posted02-Mar-2026Closing Date12-Mar-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Global Resilience Strategy and Transformation Senior Director  

    - Macclesfield
    What You’ll DoInfluence supply chain and network strategyQuantify resi... Read More
    What You’ll DoInfluence supply chain and network strategyQuantify resilience across the portfolio, including protection levels and the cost/benefit of mitigation levers (, inventory, dual sourcing, excess capacity, insurance).Provide decision support and trade-off insights that shape network design, sourcing strategies, investment allocation, and lifecycle decisions.Identify where to dial resilience up or down, prioritizing differentiated robust business cases and secure approval for significant resilience investments.Transform business continuity for Intelligent Supply and Operations 2030Lead the transformation of BCP policy, processes, tools, and ways of working—moving to a risk-based, lifecycle-aligned approach.Implement a streamlined Product BCP process supported by modern digital solutions; replace BRACE with compliant, intuitive systems that provide decision support and leverage AI in line with a self-healing supply and deploy cross-brand continuity processes to manage dependencies across products and markets.Benchmark externally to elevate AstraZeneca’s resilience capabilities and visibility.Own and govern end-to-end BCM processesServe as Business Process Owner across product, site, and functional BCM; lead multiple process networks and steering the annual BCP cycle (BIA, BCP, testing, SCAIR, EU SPP), ensuring data quality, timeliness, transparency, and clear articulation of residual risk and investment needs.Address 2025 audit actions through strengthened governance, process improvements, and system controls.Develop and maintain user-friendly, compliant digital solutions that document decisions, exceptions, and continuous improvement and maturity using lean principles.Impact You will embed risk and trade-off insights into everyday decisions so AstraZeneca delivers medicines reliably—by design, not by chance. Success in this role relies on leading cross-functional project teams and champion networks across Operations.People LeadershipLeads project teams and matrixed networks across Operations (direct and indirect leadership).Scope includes matrix management of stakeholders and process champions; formal line management may be required depending on team structure.Global ScopeOperates across multiple countries with a global remit, collaborating with teams across AstraZeneca markets and manufacturing sites.QualificationsEssentialBachelor’s years of independent, hands-on experience in supply chain expertise in supply strategy development, enterprise thinking, influencing, and relationship management.Experience in pharmaceutical operations.Demonstrated success working cross-functionally and presenting to senior leaders.Financial acumen, including product costing and business case development.Experience in risk management, business continuity management, and resilience.DesirableMaster’s degree or equivalent experience.Experience analyzing and optimizing supply chain design across inventory, capacity, and risk.Proficiency with resilience and network strategy frameworks.Experience applying lean principles.Exposure to leading-edge digital and AI-enabled supply chain solutions.Financial acumen, including product costing and business case development.Experience in risk management, business continuity management, and resilience.Working StyleOperates effectively in a matrix, balancing strategic vision with hands-on delivery.Comfortable with ambiguity and able to translate complex risk and operational data into actionable decisions for senior stakeholders.Why AstraZeneca:Be part of shaping the future of Operations here at AstraZeneca. Be part of shaping the next phase of Operations' journey towards the 2025 strategy. Build on our foundations of high performance through agility, responsiveness, reliability, and efficiency to deliver our new modalities and complex pipeline to market at speed. Backed by a supportive team, be part of accelerating our operational excellence with innovations in cutting-edge science, Lean ways of working, and fast-changing digital technologies.The annual base pay for this position ranges from $174, to $261, Annual USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.Date Posted19-Feb-2026Closing Date29-Apr-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. Read Less

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