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AstraZeneca
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  • Executive Director, AI Enterprise Process & Innovation  

    - Cambridge
    Accountabilities: Redesign critical end-to-end processes to move from... Read More
    Accountabilities: Redesign critical end-to-end processes to move from functionally optimized workflows to decision-centric models. Embed AI at the point of work.Eliminatestructural bottlenecks, manual handoffs, and decision delays to develop intelligent, streamlined operations that improve patient impact. Act as a cross-functional integrator by incubating and scaling AI-enabled use cases across functions. Develop consistent processes to move ideas from pilot to scaled enterprise capability that delivers measurable business value. Advisory Role within the Organization and Value Realization: Partner with senior leaders to compose problem statements, outline benefit scenarios, and align AI solutions with business outcomes. Collaborate alongside Finance and enterprise leaders to develop metrics, track benefits, and confirm return on onareas where AIimpactsoperating leverage compared to where traditional optimization meets needs. Collaborate with AI, data, technology, risk, quality, and legal/compliance teams to ensure solutions are scalable, secure, compliant, and ethical. Codify governance that speeds delivery without compromising safety or trust. Lead adoption using innovative operational methods. Redefine roles and improve decision-making accountability. Build enterprise understanding of AI through leadership narratives, education, and hands-on engagement. Develop talent and communities of practice passionate about process innovation, AI product thinking, and system development. Plan effectively for succession. Lead or coordinate complex, high-value AI-enabled business improvement initiatives. Orchestrate cross-functional squads to remove blockers and embed AI into daily operations. Socialize strategic outcomes bydemonstratingcost, quality, and financial improvements. Essential Skills/Experience: - Lead the redesign of important enterprise processes across the entire workflow. Transition from workflowsoptimizedfor functionality to AI-enabled, decision-focused operating models.Identifystructural bottlenecks, manual handoffs, and slow decision points. Build intelligence into workflows rather than layeringadditionaltools. - Serve as an integrator across functions by connecting business, technology, data, andchangecapabilities to achieve enterprise-wide innovation. Incubate and expand AI-enabled use cases in areas such as R&D, Manufacturing, Quality, Commercial, Medical, Legal, Finance, and Procurement. Develop repeatable methods to progress ideas from pilot to broad organizational capability. - Internal Consultancy & Value Realization: Operate as a strategic internal consultancy to senior business leaders, shaping problem statements, defining value cases, and aligning AI solutions to business outcomes; partner with Finance and business owners to define clear value metrics, track benefits realization and ROI, and ensure sustained impact; advise executives on where AI can change operating leverage vs. where traditional optimization is sufficient. - AI Operating Model & Governance: Partner with Enterprise AI, Data, IT, Risk, Quality, Legal/Compliance to ensure AI solutions are scalable, secure, compliant, and ethically deployed - Change Leadership & Capability Building: Drive adoption through new ways of working, role redesign, and decision accountability—not just technology deployment; build enterprise understanding of AI’s role in process transformation via executive storytelling, education, and hands on engagement; develop talent and communities of practice committed to process innovation, AI product thinking, and architectural planning; prepare thoughtfully for leadership continuity. - Delivery & Scale: Lead or oversee the most complex and crucial AI enabled Business Improvement initiatives to improve quality, effectiveness, and efficiency of business processes; orchestrate cross functional squads to remove blockers and embed AI capabilities into day to day operations; share strategic outcomes of key projects, outlining benefits from cost and quality perspectives and demonstrating the function’s return on investment (ROI). Desirable Skills/Experience: - Proven track record leading enterprise-scale AI-driven process transformation in complex, regulated environments. - Executive-level advisory experience, turning ambiguous problems into clear value cases and operating leverage. - Deep expertise in decision-centric operating models, process engineering, and systems design; familiarity with Lean, Six Sigma, or similar approaches. - Proficiency in AI product thinking, ML engineering and MLOps, large language models and orchestration, and data platform integration. - Experience establishing governance for responsible, secure AI in partnership with risk, quality, and legal/compliance functions. - Strong storytelling and education skills to engage senior leaders and mobilize groups ofexpertise;demonstratedsuccession planning and talent development. - Ability to orchestrate cross-functional squads and deliver from idea to pilot to scaled capability with measurable ROI. - Comfort setting direction in early-stage, ambiguous environments through experimentation and rapid learning. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challengeperceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn'tmean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Why AstraZeneca: Here, your leadership directly influences how quickly and reliably we deliver therapies to patients. You will work at the intersection of cutting-edge science and advanced digital technologies, shaping early-stage approaches and turning uncertainty into pragmatic, scalable solutions. We bring unexpected teams together to unleash bold thinking, valuing kindness alongside ambition, and empower you to build partnerships and ecosystems that create new ways of working. With the investment and autonomy to succeed, you will drive cross-company change at pace, learn fast, and see the impact of your decisions across the enterprise. Call to Action: Bring your leadership to rewire our enterprise and turn AI into everyday operating leverage—step forward and shape how life-changing medicines reach patients faster. Date Posted19-Jan-2026Closing Date08-Feb-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Principal AI Engineer - Evinova  

    - London
    Principal AI Engineer - EvinovaLocation: London, UKIt currently takes... Read More
    Principal AI Engineer - EvinovaLocation: London, UKIt currently takes over 10 years and $ to develop a drug. More than 70% of that investment goes into clinical trials, yet only ~10% of candidates make it from Phase I to approval.Evinova - a new health-tech business within the AstraZeneca Group—is here to change the math. We use advanced algorithms and GenAI to aim high: boosting clinical trial success by 20%, cutting development time by 3 years, and halving study costs.We are looking for a highly skilled Principal AI Engineer who combines strong coding expertise with curiosity and business acumen. In this role, you will not only build advanced algorithms and agentic AI but also ensure your technical work directly supports company targets, working on both internal initiatives and client/ consulting-style engagements. You will bring a value-driven mindset, using critical analysis to ensure outcomes align with business goals. WHAT THE ROLE INVOLVESAI DEVELOPMENT & ARCHITECTURE – You will build sophisticated GenAI, Machine Learning and Optimization solutions tailored to the life sciences, taking them from initial PoC through to full industrialization.ENGINEERING & DEPLOYMENT – Deliver high-quality and production-ready code, supporting deployment on the cloud (AWS). You will support the development of robust data pipelines, focusing on flexibility to ensure smooth integration with various client data ecosystems.BUSINESS ENGAGEMENT - You will present the progress of AI initiatives, gather feedback, and translate complex technical outcomes into clear business value for senior leadership and stakeholders.CROSS-FUNCTIONAL INNOVATION - Thrive in a dynamic ecosystem where AI, Product, Strategy, and UX intersect. You will act as a key translator, connecting cutting-edge AI capabilities with real-world Pharmaceutical requirements to deliver meaningful digital transformation.SKILLS AND CAPABILITIES NEEDEDWhat You Bring:EXPERIENCE - 5+ years designing novel algorithms and applied AI/ML solutions that drove measurable business impact.GENERATIVE AI EXPERTISE - Experience building GenAI solutions for real-world use cases, with a solid grasp of agentic AI frameworks (LangChain, Google GenAI SDK, LlamaIndex, etc.).MODERN TECH STACK - Expert knowledge of Python and standard data frameworks (pandas, scipy, etc.). Expertise in leveraging GenAI coding assistants (GitHub Copilot, Cursor, etc.) to accelerate development cycles.ENGINEERING RIGOR - A proven track record of shipping production-level code using software engineering best practices.COMMUNICATION - Excellent verbal and written communication skills, with experience presenting technical concepts to non-technical stakeholders with clarity.Nice to Have:INFRASTRUCTURE - Familiarity with AWS services, AWS CDK, Containerization, and CI/CD pipelines.PHARMA INDUSTRY KNOWLEDGE: Previous experience in Life Sciences is desirable, but not mandatory.CONSULTING - Experience interacting with high-level business stakeholders or working in a consultancy environment.Why Evinova (AstraZeneca)?Evinova draws on AstraZeneca’s deep experience developing novel therapeutics, informed by insights from thousands of patients and clinical researchers. Together, we can accelerate the delivery of life-changing medicines, improve the design and delivery of clinical trials for better patient experiences and outcomes, and think more holistically about patient care before, during, and after treatment. We know that regulators, healthcare professionals, and care teams at clinical trial sites do not want a fragmented approach. They do not want a future where every pharmaceutical company provides its own, different digital solutions. They want solutions that work across the sector, simplify their workload, and benefit patients broadly. By bringing our solutions to the wider healthcare community, we can help build more unified approaches to how we all develop and deploy digital technologies, better serving our teams, physicians, and ultimately patients. Evinova represents a unique opportunity to deliver meaningful outcomes with digital and AI to serve the wider healthcare community and create new standards for the sector. Join us on our journey of building a new kind of health tech business to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting-edge methods, and bringing unexpected teams together. Interested? Come and join our journey.So, what’s next?Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.Where can I find out more?Our Social Media, Follow Evinova on LinkedIn Learn more about Evinova Date Posted15-Jan-2026Closing Date30-Jan-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Personal Assistant – Group Controller & Global Finance Services (12-mo... Read More
    Personal Assistant – Group Controller & Global Finance Services (12-month secondment/FTC)Location: LutonAbout AstraZenecaAt AstraZeneca we believe in the potential of our people, and you’ll develop beyond what you thought possible. We make the most of your skills and passion by actively supporting you to see what you can achieve no matter where you start with us.Are you ready to take on a pivotal role that supports the leadership of a global finance function? In this role you will provide support to members of the GC GFS leadership team, providing high-level administrative support while collaborating with a dynamic administrative team.Your organisational and communication skills will be crucial as you ensure attention to detail and perseverance in completing tasks. You'll engage with team members from diverse cultures, building networks and supporting colleagues. Adaptability and composure are key as you respond to changing demands with a consistent focus on high-quality work.Key Responsibilities:Proactive diary management and adaptable to short notice changes and conflicts.Proactive planning of travel arrangements, including flights, accommodation, airport transportation, car bookings, trains, visa requirements etc. (preparing travel packs / itineraries where required).Collating and processing of expense claims within set group timelines and ensuring compliance with the expenses policy.Coordinating internal/external meetings including room bookings and catering arrangements, coordinating global conference calls / video conference calls.Supporting department updating and maintaining all distribution lists, organisational charts and other relevant documentations.An integral member of the UK GC GFS PA cohort, collaborating with colleagues to provide mutual support and assisting in the organisation of UK team engagements.Co-ordinates and collates detailed information with effective and clear communication to relevant stakeholders.Understand and always adhere to the AstraZeneca Global Code of Conduct, AZ and Global policies.
    Requirements:Experience of providing full PA/administrative support at a senior level.Confident and experienced using Microsoft Office, Teams, and a wide variety of technology and IT softwares.Experience in raising purchase requisitions / orders and vendor creation.Excellent written and verbal communication skills.Excellent administrative, time management and organisational skills.Collaborative teammate, with excellent interpersonal skills.Ability to effectively handle multiple priorities and a high level of resilience and self-motivation.Excellent team working, networking and influencing skills and ability to engage relevant AstraZeneca stakeholders and other PA/EAs.Ability to work autonomously with independent judgement and discretion and handling confidential information where applicable.
    In Office Requirement:When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
     Why AstraZeneca?At AstraZeneca, we blend medical expertise with commercial competence to pioneer innovative ways that better serve our patients. Our commitment to science and ethics drives us to launch cutting-edge products into our growing healthcare ecosystem. We thrive on creativity and imagination, always supported by a strong foundation of ethics. As part of our global network, you'll have the opportunity to learn from world-class people and work with new and innovative drugs. Our science-led pipeline empowers us to make a profound difference in patients' lives, offering you a meaningful career filled with unexpected opportunities.Date Posted15-Jan-2026Closing Date30-Jan-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Process Improvement Lean Facilitator (SF&A) - Nights Friday to SundayL... Read More
    Process Improvement Lean Facilitator (SF&A) - Nights Friday to SundayLocation: MacclesfieldPermanent Nights - 38 hours per weekAt AstraZeneca, we’re redefining what a bio-pharmaceutical company can achieve. Our innovative approach opens up new ways to work, pioneering groundbreaking methods and bringing unexpected teams together. Join us as a Process Improvement Lean Facilitator - Nights upon Syringe Fill & Assembly at our sterile manufacturing plants on the expansive Macclesfield campus, where we're driving ambitious redevelopment grounded in Chemistry, Packing, and Complex Parenterals.Are you ready to lead continuous improvement at the heart of night shift manufacturing, accelerating quality batch release and raising performance where it matters most? In this role, your lean leadership will translate bold ambition into day-to-day results, strengthening safety, quality, supply, cost and people outcomes while shortening the path from molecule to medicine.You will be the trusted facilitator for the plant improvement portfolio during night operations, partnering with Production Leads, Improvement/Reliability Engineers and the business area to prioritise resources against the wider scorecard. Your work will improve organisational strength and create a solid “Right from me” quality culture. It will ensure seamless coordination with Quality to deliver products to patients while maintaining compliance.Accountabilities:Lean Leadership Coaching: Develop an environment that supports lean leadership. Mentor teams to adopt lean methods that improve safety, quality, delivery, and cost.Night Shift Improvement Portfolio: Serve as the night shift contact in the plant improvement portfolio process, collaborating with Production Leads, Improvement/Reliability Engineers and the business area to prioritise and deploy resources that lift performance against the scorecard.Change Management and Compliance: Support change management activities, contribute to impact assessments, and provide technical expertise on potential effects to procedural and manufacturing compliance.SQSCP Performance Monitoring: Monitor SQSCP performance for assets and production teams; react proactively to signals to protect stability and accelerate recovery.Continuous Improvement Culture: Coach production teams to embed lean and continuous improvement methodologies across night operations, fostering a culture of operational excellence.Self-Inspection and QMS Compliance: Perform self-inspections to confirm compliance with approved procedures, processes and AstraZeneca Quality Management Systems; address non-conformance and track actions to timely completion.Structured Problem-Solving: Provide expertise using structured methodologies to address complex operational challenges, translating root causes into sustainable countermeasures.Kaizen Leadership: Lead and support Kaizen sessions and collaborative workshops to drive rapid improvement and engage cross-functional teams in practical problem-solving.Lean Maturity Reviews: Conduct lean maturity reviews to identify gaps and opportunities for improvement, shaping a clear path to higher performance.Cross-Functional Improvement: Identify and scope cross-functional improvement projects to increase plant utilisation and deliver unconstrained customer supply.Essential Skills/Experience:Experience embedding a culture of lean leadership and coaching teams in lean ways of working.Proven facilitation skills across production, improvement/reliability engineering and business area to prioritise and deploy resources effectively.Ability to support change management, perform impact assessments and advise on procedural and manufacturing compliance.Strong communicator able to act as a bridge between production and Quality to enable efficient batch release.Experience coaching production teams to embed continuous improvement methodologies.Experience conducting self-inspections against approved procedures, processes and Quality Management Systems, with a focus on corrective action follow-through.Working knowledge of GMP and ALCOA+ principles with experience reviewing manufacturing batch records for compliance.Expertise in structured problem-solving methodologies to address complex operational challenges.Experience leading and supporting Kaizen events and workshops to drive rapid improvement.Demonstrated ability to implement local lean strategy and champion assigned workstreams.Ability to conduct lean maturity reviews to identify gaps and opportunities for improvement.Desirable Skills/Experience:Lean Six Sigma certification or formal lean coaching accreditation.Familiarity with visual management and digital tools supporting SQSCP monitoring and daily management.Demonstrated success leading cross-functional transformations and scaling improvements across multiple teams or sites.Direct experience with PET portfolio processes and alignment to enterprise scorecards.At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development. Interested? Come and join our journey!Date Posted15-Jan-2026Closing Date31-Jan-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Associate Principal Scientist (APS), Conjugation Scientist  

    - Cambridge
    Associate Principal Scientist (APS), Conjugation ScientistCambridge UK... Read More
    Associate Principal Scientist (APS), Conjugation Scientist
    Cambridge UK (On-site)About AstraZenecaAstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we are pioneering new frontiers by identifying and treating patients earlier, working towards the aim of eliminating cancer as a cause of death.Come and join our AZ team where you will play a pivotal role in this exciting period of development!As an Associate Principal Scientist, you'll spearhead the development of innovative bioconjugates, pushing the boundaries of science to develop life-changing medicines. Join us in exploring new frontiers and making a significant impact on global healthcare.Key Responsibilities:Lead antibody-based conjugation projects for both technology development and inclusion in our bioconjugate portfolio.Conceive, design, and synthesise high‑quality antibody conjugates Antibody-drug conjugates (ADCs), bispecifics/tri‑specifics conjugates etc) using lysine, cysteine, engineered‑cysteine and enzymatic chemistries.Select payloads and rationally design conjugate architectures to optimize stability, payload antibody ratios (DAR/PAR/OAR), pharmacology, and on‑target potency balance and efficacy.Lead hands‑on expression, conjugation and purification at small‑ to mid‑scale material (up to gram‑scale), establish robust SOPs, and deliver materials to internal stakeholders on schedule.Express and characterise antibodies, VHHs and fusion constructs; perform Bioconjugation, binding assays, and developability assessments.Extensive experience in protein engineering related to antibody conjugate optimization such as half-life extension, effector silencing, Fc engineering for thermal stabilityOwn analytical QC across SEC, HIC, RP‑HPLC, IEX, native and denaturing SEC‑MSPartner with cross‑functional teams (, Therapy area partners, senior leaders, protein engineering, bioanalytics, pharmacology) to set experimental strategy, interpret data, and move programs through appropriate milestonesContribute to IP (inventions/patents) and publications; present at internal governance and external conferences.Mentor junior scientists and (where applicable) and matrix manage pipeline and technology projects in support of antibody-conjugates by championing high standards in safety, quality, and scientific rigour.Requirements:PhD (or equivalent) in Chemical Biology, Biochemistry, Pharmaceutical Sciences, Chemistry or a related field and 8 years’ hands‑on experience in bioconjugation/ADCs in Biotech/PharmaDemonstrated track record progressing conjugate therapeutics (, ADCs etc) through key discovery gates and into preclinical development.Deep expertise in bioconjugation chemistries (lysine, cysteine/engineered cysteine, enzymatic); ability to tailor conjugation routes to format, payload, and developability constraints.Payload selection and linker–payload design (cleavable/non‑cleavable; acid‑labile, enzyme‑cleavable; rebridging and site‑specific strategies); strong SAR approach.Protein expression and purification (IgG, VHH, fusion constructs) with hands‑on experience in bioconjugation, purification, and QC release.Mastery of analytics: SEC/HIC/RP‑HPLC/SAX; LC‑ESI‑MS (native SEC‑MS and denaturing RP‑MS); data analysis and interpretation for batch release and comparability.Proven ability to lead deliverables, communicate progress to cross‑functional leadership, and present complex results to governance/senior stakeholders.Exposure to Fc‑engineering (, FcγR mutations, half‑life modulation) with cell assay execution.Familiarity with display technologies and protein engineering concepts to support conjugation site selection and format designExperience authoring patents/manuscripts and contributing to articles & grants; effective scientific writing.Desirables: Experience in application of AI design methodologies for bioconjugate development payload site placement, conjugation efficiency, developability or stabilityFunctional and primary cell assay design and execution (ADCC/ADCP; internalisation; efferocytosis) and associated data analysis/statistics.Familiarity with dual‑payload strategies and rebridging approaches.Broad bioassay toolkit: reporter assays (luciferase/SEAP), flow‑based internalisation, confocal imaging, Incucyte‑based live‑cell readouts.In Office Requirement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of five days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.Why AstraZeneca? At AstraZeneca's Oncology R&D business area, you'll be part of a team playing a critical role in driving meaningful change in the way we predict, prevent and treat patients' conditions. We're actively embracing and investing in technology, harnessing digital, data and analytics to reimagine the future of healthcare and deliver improved outcomes to patients beyond core medical. We're shaping the future, improving and speeding up portfolio development, improving the patient experience and outcomes at clinical trials. Join the team that is co-creating a digital ecosystem with patients at its core.Competitive salary and benefits package on offer.The successful candidate will have access to a flexible employee benefits fund, including holiday purchase and flexible time off, pension contributions, Share Save Plans, A performance recognition scheme and a competitive, generous remuneration package.Date Posted15-Jan-2026Closing Date23-Jan-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Level 6 Laboratory Scientist Degree Apprenticeship- QC & Microbiology  

    - Macclesfield
    Level 6 Laboratory Science Degree Apprenticeship – QC & MicrobiologyMa... Read More
    Level 6 Laboratory Science Degree Apprenticeship – QC & MicrobiologyMacclesfield, UK Starting base salary of £24,570+ 11% benefits fund + bonusAt AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. We are deeply committed to our strategy of being a great place to work. For us, that includes fostering an environment where everyone can be among inclusive, supportive individuals with curious minds. A company that genuinely follows the science and values individuals at all levels, you will be backed and encouraged to speak up, ask questions, and share ideas to push the boundaries of science and continuously learn and explore. Make the start of your journey a life changing one As part of our Early Talent Programme, you will be involved in projects and learning opportunities that have real impact from day one. Being part of our journey and helping us to provide life changing medicine to patients all over the world and transform lives for the better. Making important contributions and embracing our values to deliver on our purpose. Because regardless of role or level, we all have an important part to play in making a positive difference. Macclesfield  The Macclesfield Campus is an essential part of AstraZeneca’s UK Operation and the 2nd largest operational site within the company’s global network. It is approx. 100 acres with around 4500 people working on site. The site is unique in the AstraZeneca network having Operations, R&D, G&A, IT and others on its site. About the Apprenticeship Programme  We are offering Laboratory Scientist Apprenticeships within the QC, QA or PT&D Microbiology areas. You'll be working with scientists across different lab teams and production facilities to undertake development microbiological testing of raw materials, water systems and finished products. Our teams partner closely with manufacturing to provide timely data, technical insight, and compliance support that keeps operations running safely and to exacting standards. Within QC Microbiology, you will gain exposure to three core areas: Process Assurance: Collection, trending, and interpretation of environmental monitoring data across manufacturing areas—supporting contamination control, aseptic assurance, and timely investigation input. Product Quality: Execution of routine microbiological assays on raw materials, in-process samples, water, and finished products—including bioburden, endotoxin, water activity, and sterility testing—ensuring batches meet specifications prior to release. Water, Support, and Identification (WSI): Monitoring and qualification of site water systems against quality requirements, microbial identification of isolates using multiple technologies, and provision of sterile equipment and media to enable environmental monitoring and product testing. Quality control is our top priority. As a QC Microbiology apprentice, you will develop hands-on laboratory skills, understand GMP and data integrity principles, and contribute to the reliable delivery of results that underpin product release decisions and support the wider manufacturing teams. Who this suits;Structured & consistent: You enjoy a predictable workday with clear procedures, set schedules, and defined quality standards.Detail-focused: You take pride in repeating tasks to the same high standard, spotting anomalies, and preventing errors.Process-minded: You are comfortable with checklists, version-controlled SOPs, and standardized documentation.This is a hands-on quality role, ideal for someone who values routine and precision. You’ll perform recurring QC tests, follow established SOPs, and document results in accordance with regulatory requirements. Success in this role comes from consistency, attention to detail, and dependable execution. If you find satisfaction in delivering the same high-quality outputs day after day—and improving them through small, compliant refinements—this role will suit you.AstraZeneca will sponsor you through a BSc Degree in Applied Biosciences with Manchester Metropolitan University The apprenticeship combines working, earning a full-time salary, with fully funded part-time university learning (on average 1 day/week). This will give you the opportunity to gain a BSc Degree in Applied Biosciences qualification, just as you would if you went to university full-time, with the advantage of gaining relevant work-life skills and the excitement of helping to develop new medicines whilst taking your first steps towards a rewarding career.Additionally, you’ll be recognised by the relevant professional bodies at Registered Scientist (RSci) level, for which there is a requirement that the scientist will participate in subsequent continuing professional development on completion of the apprenticeship.We truly value Early Talent– their thoughts, ideas and contributions. So throughout the programme, you’ll be encouraged and inspired to speak up, have a voice and make an impact.Essential skills/capabilities required:Good communication skillsGood team working skillsHigh organisation skills and confidence to work independentlyThe ability to apply a rational approach to problem solving; making judgements based on sound reasoning, approaching problems in a logical mannerConcerns for standardsWillingness to work in aseptic manufacturing facilitiesHigh numeracy and literacy skillsComputer literacyThe ability to learnSelf-motivationInitiativeEntry Requirements: Five GCSEs (or equivalent) grades 9–4 including Maths, English and Science. Applicants should have or be predicted to achieve a minimum of 104 UCAS points at A-level (grades BCC), with one being Biology or an equivalent scientific discipline. Candidates with relevant workplace experience or a BTEC Level 3 Extended Diploma in a related scientific discipline will also be considered but must provide additional details of their experience / units studied on the course as part of their application Benefits, open and close dates To apply for this position, please click the apply link. Opening date of advert: 12th January 2026 Closing date of advert: midnight 15th February 2026 Successful candidates will be asked to attend a virtual Assessment Day on 24th and 25th March. Should you require any reasonable adjustments or accommodations, please let us know on your application. Start date for the apprenticeship programme is 7th September 2026 This is a 4 year fixed term opportunityAt AstraZeneca, we aim to set you up for success and we recognise the challenges that starting a new job can bring. We therefore offer a relocation package to help with the costs and process of moving for candidates who currently live more than 60 minutes from the site location for this Apprenticeship. Where can I find out more? Our Social Media, Follow AstraZeneca on LinkedIn: Inclusion & Diversity:  Career Site: AstraZeneca is proud to be ranked as a Top 100 ‘Best Student Employer’ in the UK by RateMyPlacement. Browse our reviews here () These positions are not open to those already educated to Bachelor's degree level or above – for which we have specific Graduate Programmes, see our website for more details  #EarlytalentDate Posted12-Jan-2026Closing Date15-Feb-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Automation Support Engineer – Night Shift  

    - Macclesfield
    Automation Night Shift EngineerMacclesfield This will be a permanent n... Read More
    Automation Night Shift EngineerMacclesfield This will be a permanent night-shift position working a 4 on, 4 off rotation (10 hours per shift 20:00-06:00)Introduction to role:Join our dynamic shift-team at AstraZeneca Macclesfield. As an Automation Night Shift Engineer, you will play a crucial part of the Zoladex manufacturing and sterile packaging systems, providing 24/7 support to ensure the smooth operation of automated and computerised systems. Your role will involve troubleshooting and resolving issues with automation equipment and control systems, performing proactive and reactive maintenance, and implementing technical solutions to optimise production efficiency and ensure compliance with regulatory and quality standards.Accountabilities:Your role will involve delivering and sustaining business objectives, providing engineering and automation expertise, to maintain equipment and systems by resolving problems and implementing well as planning, coordinating, and undertaking electrical and control system maintenance activities; will be required to respond to critical breakdowns in a timely manner and maximising equipment availability.You will be driving continuous improvement, by conducting and coordinating investigations identifying root cause analysis, and implementing effective containments and well as working closely with the plant maintenance technicians; you will be supporting theirknowledge uplift of automated systems; along with your own development.Essential Skills/Experience:Recognised Engineering Apprenticeship or equivalentONC/HNC or equivalent in a relevant engineering fieldExperience with Electrical and instrumentation systemsExperience with PLC, HMI, Robotic and Automation systems ( Siemens S7, TIA, WinCC, Schneider, Staubli)Desirable Skills/Experience:Bachelor’s Degree in Engineering or equivalent professional qualificationPLC programming certification Experience with Windows O/S and SQLExperience with industrial networks ( Industrial Ethernet / PROFINET)Previous pharmaceutical industry experience and understanding of cGMP maintenance practicesMember of a relevant professional bodyAt AstraZeneca, we are driven by innovation and our commitment to deliver life-changing medicines. With constant new products and launches, there's never been a better time to join our Supply Chain team. We thrive on challenges and continuously seek new and better ways to deliver medicines all the way to our patients. Our resilience helps us to innovate and evolve in rapidly changing markets. We foster a safe and positive space where ideas are welcomed and rewarded. If you are driven, take smart risks and are able to act quickly, then this is the place for you.Ready to make a difference? Apply now to join our team!Date Posted13-Jan-2026Closing Date25-Jan-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Level 3 Process Industry Manufacturing Technician Apprentice  

    - Macclesfield
    Level 3 Process Industry Manufacturing Technician ApprenticeMacclesfie... Read More
    Level 3 Process Industry Manufacturing Technician ApprenticeMacclesfield, UK Starting base salary of £24,570+ 11% benefits fund + bonusAt AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. We’re deeply committed to our strategy of being a great place to work. For us, that includes fostering anenvironment where everyone can be among inclusive, supportive individuals with curious minds.A company that genuinely follows the science and values individuals at all levels, you’ll be backedand encouraged to speak up, ask questions, and share ideas to push the boundaries of science andcontinuously learn and explore.Make the start of your journey a lifechanging oneAs part of our Early Talent Programme, you’ll be involved in projects and learning opportunities that have real impact from day one.Being part of our journey and helping us to provide life changing medicine to patients all over the world and transform lives for the better. Making important contributions and embracing our values to deliver on our purpose. Because regardless of role or level, we all have an important part to play in making a positive difference.MacclesfieldThe Macclesfield Campus is an essential part of AstraZeneca’s UK Operation and the 2nd largest operational site within the company’s global network. It is approx. 100 acres with around 4500 people working on site. The site is unique in the AstraZeneca network having Operations, R&D, G&A, IT and others on its site.About the Apprenticeship ProgrammeThe apprenticeship programme will be manufacturing based learning with practical on the job training within the Zoladex/Copolymer manufacturing departments. There will be opportunities to rotate between plants and different products working alongside industry professionals to gain a broad experience of each department including time spent shadowing the Health & Safety advisers. Carrying out duties such as:Delivering the required production demand for a number of pharmaceutical products. Operation of manufacturing equipment, including start up and shutdown procedures, in process checks. Performing critical quality checks in line with current Good Manufacturing Procedures (cGMP)Use of Lean manufacturing toolsThere are two key Manufacturing areas of Macclesfield Site, the Global Packaging centre of excellence and the Sterile Parenteral Manufacturing Area. These are both highly regulated working environments where we produce & pack medicines for patients. Due to the nature of the regulated working environment, you will be trained in how to dress and operate effectively & efficiently. You'll work either a Monday to Friday day pattern or a shift pattern as follows:6am to Monday to Thursday and 6am to 12 noon on Friday to Monday to Thursday and 12 noon to 6pm on FridayWhilst routinely our Apprentices are not required to support working weekends some aspect of this may be planned in as part of the apprenticeship to support the apprentices learning and experience if placed in an area that works that pattern. Shift working receives additional payments dependent on the type of shift pattern worked.Training and DevelopmentAstraZeneca will sponsor you through yourLevel 4 Process Industry Manufacturing Technician qualification through Cogent. The apprenticeship combines working, earning a full-time salary, with fully funded part-time learning (on average 1 day/week). This will give you the opportunity to gain aLevel 4 Process Industry Manufacturing Technicianqualification, just as you would if you went to college full-time, with the advantage of gaining relevant work-life skills and the excitement of helping to develop new medicines whilst taking your first steps towards a rewarding career.We truly value Early Talent– their thoughts, ideas and contributions. Throughout the programme, you’ll be encouraged and inspired to speak up, have a voice and make an impact.Skills and CapabilitiesWe would be looking for the following attributes from our successful applicants:Good communication & team working skillsHigh organisation skills and confidence to work independentlyLogical thinking to be able to apply processesAbility to apply a rational approach to problem solving; making judgements based on sound reasoning, approaching problems in a logical mannerHigh numeracy and literacy skills including computer literacySelf-motivated and able to work on own initiativeEntry Requirements5 GCSEs (or equivalent) grades 9 to 4 including English and Maths.To have achieved or predicted to achieve a minimum of 1A levels at Grade C (32 UCAS points) or equivalent at Grade C.Benefits, open and close datesTo apply for this position, please click the apply link.This is a 3-year fixed term contract opportunity based at Macclesfield with a starting base salary of £24,570+ 11% benefits fund + bonus.At AstraZeneca, we aim to set you up for success and we recognise the challenges that starting a new job can bring. We therefore offer a relocation package to help with the costs and process of moving for candidates who currently live more than 60 minutes from the site location for this Apprenticeship. Opening date of advert: 12thJanuary 2026Closing date of advert: 15th February 2026Successful candidates will be asked to attend a virtual Assessment Day during week commencingShould you require any reasonable adjustments or accommodations, please let us know on your application.Start date for the apprenticeship programme is 7th September 2026Equal Opps Read Less
  • Level 6 Laboratory Scientist Degree Apprenticeship-Biopharmaceuticals R&D  

    - Cambridge
    Level 6 Laboratory Scientist Degree Apprenticeship – Biopharmaceutical... Read More
    Level 6 Laboratory Scientist Degree Apprenticeship – Biopharmaceuticals R&DCambridge, UKStarting base salary of £24,570 + 11% benefits fund + bonusAt AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. We’re deeply committed to our strategy of being a great place to work. For us, that includes fostering an environment where everyone can be among inclusive, supportive individuals with curious minds.A company that genuinely follows the science and values individuals at all levels, you’ll be backed and encouraged to speak up, ask questions, and share ideas to push the boundaries of science and continuously learn and explore.Make the start of your journey a life changing one!As part of our Early Talent Programme, you’ll be involved in projects and learning opportunities that have real impact from day one.Being part of our journey and helping us to provide life changing medicine to patients all over the world and transform lives for the better. Making important contributions and embracing our values to deliver on our purpose. Because regardless of role or level, we all have an important part to play in making a positive difference.Cambridge  Cambridge is one of the most exciting bioscience hotspots in the world. The Discovery Centre (DISC), located at the heart of the Cambridge Biomedical Campus, is designed to play a central role in our mission to deliver life-changing medicines to patients. As our largest research and development centre in the UK, it will have more than 2,000 people working across therapy areas and drug discovery and development once fully occupied. About the Apprenticeship ProgrammeWe have three opportunities available in our Biopharmaceuticals R&D function. Please see below for more details and indicate any preferences on your application:Cell Engineering - Discovery SciencesAs part of the Cell Engineering team within Discovery Sciences, you'll use innovative gene editing technologies to generate modified cancer cell lines for target identification, target validation and drug development in the Oncology disease area. You'll gain extensive expertise in the use of the revolutionary genome editing technology, CRISPR, to specifically alter the DNA of cancer cells, creating novel cellular models that will enable characterisation of oncological pathways. As part of this innovative team you'll have the opportunity to improve current CRISPR methods for use in preclinical model generation. As well as learning best practise cell culture techniques and various modes of gene editing, you will acquire skills in characterising gene sequences and protein expression such as digital PCR, western blotting and flow cytometry. Early Stage Formulation ScienceYou will join the Early-Stage Formulation Sciences team, where the goal is to develop stable, effective, and safe formulations for biological products, ensuring their compatibility with delivery systems and adherence to regulatory standards for successful commercialization. In this role, you will focus on supporting candidate selection and candidate development for non-clinical and clinal development. Leveraging automation to enhance these processes and guided by scientists, you will champion the design and execution of formulation strategies across a wide range of modalities.Key Responsibilities:Cultivate analytical skills and scientific expertise with the aim of becoming a proficient formulation scientistWork collaboratively with team members and cross-functional teams to perform physico-chemical characterization of lead candidates, developability and manufacturability studies, formulation screening and robustness studies, clinical in-use studies.Contribute to the preparation of technical reports and presentations, showcasing achievements and promoting activities to the broader team and AstraZeneca colleagues.Early CVRMAs part of the Renal Bioscience team within early CVRM, you’ll design and execute experiments in renal in advanced, 3D vitro models to evaluate the efficacy and mechanisms of novel drug candidates addressing unmet needs in kidney disease. You will gain and apply proficiency in key analytical techniques—including qPCR, Western blot, and quantitative imaging assays. CVRM is the combination of cardiovascular, renal and metabolism studies at AZ. Working in this highly collaborative environment, you’ll communicate findings clearly through presentations and written outputs, contribute to method innovation, and help advance drug discovery within a pharmaceutical setting.Training and DevelopmentAstraZeneca will sponsor you through your Laboratory Science Degree with our university provider Manchester Metropolitan University.The apprenticeship combines working, earning a full-time salary, with fully funded part-time learning (on average 1 day/week). This will give you the opportunity to gain a Level 6 Lab Science degree qualification, just as you would if you went to university full-time, with the advantage of gaining relevant work-life skills and the excitement of helping to develop new medicines whilst taking your first steps towards a rewarding career.We truly value Early Talent– their thoughts, ideas and contributions. So throughout the programme, you’ll be encouraged and inspired to speak up, have a voice and make an impact.Skills and CapabilitiesWe would be looking for the following attributes from our successful applicants:Enthusiastic individuals who are keen to learn and with a genuine scientific curiosityAble to act independently but also to work and contribute in a team environmentGood organisational skills with an excellent attention to detail & a proactive approach to problem solvingThe ability to work on multiple tasks and understanding how to prioritiseExcellent verbal and written communication and interpersonal skillsEntry RequirementsFive GCSEs (or equivalent) grades 9 to 5 including Maths, English and ScienceTo have achieved or predicted to achieve a minimum of 104 UCAS points at A-level (grades BCC) with at least one subject being Biology or an equivalent science based discipline ( BTEC DMM/T-Levels considered).Open and close datesTo apply for this position, please click the apply link.Opening date of advert: 12th January 2026Closing date of advert: midnight 15th February 2026Successful candidates will be asked to attend a virtual Assessment Day on 26th March 2026At AstraZeneca, we aim to set you up for success, and we recognise the challenges that starting a new job can bring. We therefore offer a relocation package to help with the costs and process of moving for candidates who currently live more than 60 minutes from the site location for this Apprenticeship.This is a 4 -year fixed term contract opportunity.Start date for the apprenticeship programme is 7th September 2026Where can I find out more?Our Social Media, Follow AstraZeneca on LinkedIn: Inclusion & Diversity: Career Site: These positions are not open to those already educated to Bachelor's degree level or above – for which we have specific Graduate Programmes, see our website for more details #EarlytalentDate Posted12-Jan-2026Closing Date15-Feb-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less
  • Level 6 Laboratory Scientist Degree Apprenticeship – Biopharmaceutical... Read More
    Level 6 Laboratory Scientist Degree Apprenticeship – Biopharmaceutical Development & Centre for Genomics ResearchCambridge, UKStarting base salary of £24,570 + 11% benefits fund + bonusAt AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. We’re deeply committed to our strategy of being a great place to work. For us, that includes fostering an environment where everyone can be among inclusive, supportive individuals with curious minds.A company that genuinely follows the science and values individuals at all levels, you’ll be backed and encouraged to speak up, ask questions, and share ideas to push the boundaries of science and continuously learn and explore.Make the start of your journey a life changing one!As part of our Early Talent Programme, you’ll be involved in projects and learning opportunities that have real impact from day one.Being part of our journey and helping us to provide life changing medicine to patients all over the world and transform lives for the better. Making important contributions and embracing our values to deliver on our purpose. Because regardless of role or level, we all have an important part to play in making a positive difference.Cambridge  Cambridge is one of the most exciting bioscience hotspots in the world. The Discovery Centre (DISC), located at the heart of the Cambridge Biomedical Campus, is designed to play a central role in our mission to deliver life-changing medicines to patients. As our largest research and development centre in the UK, it will have more than 2,000 people working across therapy areas and drug discovery and development once fully occupied. About the Apprenticeship ProgrammeCentre for Genomics ResearchThe Functional Genomics department in AstraZeneca’s Centre for Genomics Research helps discover new drug targets by using advanced screening and validation technologies. Our work supports AstraZeneca’s medicine pipeline, and the team has a strong track record of impact.As a Laboratory Science Apprentice, you’ll learn hands-on lab skills and develop digital skills in data analysis while contributing to next‑generation phenotypic screening platforms that identify and validate novel drug targets. You’ll work closely with scientists across the Centre for Genomics Research and with therapy area teams, including oncology.What you’ll doLearn and perform lab experiments: Build skills in cell biology and molecular biology; help develop, optimise, and run cell-based and phenotypic assays. You will be trained in techniques such as CRISPR-Cas9, working in miniaturised plate formats under supervision.Support innovation and optimisation: Keep up to date with new scientific approaches in CRISPR screening, genome engineering, and functional genomics. Apply improvements to assays that help discover targets across multiple therapy areas.Collaborate and communicate: Work within cross-functional teams, share results clearly, and build networks across different disease areas and scientific disciplines.Biopharmaceutical DevelopmentWorking with diverse and novel molecular modalities across all therapeutic areas, Biopharmaceutical Development (BPD) integrates cell biology, process science, molecular structure & function, solution and solid-state chemistry, advanced data analytics, and engineering, to develop industry-leading technologies.BPD’s innovative science enables high-yielding, efficient production for the most challenging and novel biologics, as well as delivery of new medicines through design of stable formulations and development of drug delivery systems. With device development, BPD is creating products with a patient-centric mind-set, transforming Research Molecules into new life-changing Medicines.You will join the Early-Stage Formulation Sciences team, where the goal is to develop stable, effective, and safe formulations for biological products, ensuring their compatibility with delivery systems and adherence to regulatory standards for successful commercialization. In this role, you will focus on supporting candidate selection and candidate development for non-clinical and clinal development. Leveraging automation to enhance these processes and guided by scientists, you will champion the design and execution of formulation strategies across a wide range of modalities.Key Responsibilities:Cultivate analytical skills and scientific expertise with the aim of becoming a proficient formulation scientistWork collaboratively with team members and cross-functional teams to perform physico-chemical characterization of lead candidates, developability and manufacturability studies, formulation screening and robustness studies, clinical in-use studies.Contribute to the preparation of technical reports and presentations, showcasing achievements and promoting activities to the broader team and AstraZeneca colleagues.Training and DevelopmentAstraZeneca will sponsor you through your Laboratory Science Degree with one of our university providers- North Eastern University London The apprenticeship combines working, earning a full-time salary, with fully funded part-time learning (on average 1 day/week). This will give you the opportunity to gain a Level 6 Lab Science degree qualification, just as you would if you went to university full-time, with the advantage of gaining relevant work-life skills and the excitement of helping to develop new medicines whilst taking your first steps towards a rewarding career.We truly value Early Talent– their thoughts, ideas and contributions. So throughout the programme, you’ll be encouraged and inspired to speak up, have a voice and make an impact.Skills and CapabilitiesWe would be looking for the following attributes from our successful applicants:Enthusiastic individuals who are keen to learn and with a genuine scientific curiosityAble to act independently but also to work and contribute in a team environmentGood organisational skills with an excellent attention to detail & a proactive approach to problem solvingThe ability to work on multiple tasks and understanding how to prioritiseExcellent verbal and written communication and interpersonal skillsEntry RequirementsFive GCSEs (or equivalent) grades 9 to 5 including Maths, English and ScienceTo have achieved or predicted to achieve a minimum of 104 UCAS points at A-level (grades BBB) with at least one subject being Biology or an equivalent ( BTEC DMM/T-Levels considered).Open and close datesTo apply for this position, please click the apply link.Opening date of advert: 12th January 2026Closing date of advert: midnight 15th February 2026Successful candidates will be asked to attend a virtual Assessment Day 18th March 2026At AstraZeneca, we aim to set you up for success, and we recognise the challenges that starting a new job can bring. We therefore offer a relocation package to help with the costs and process of moving for candidates who currently live more than 60 minutes from the site location for this Apprenticeship.This is a -year fixed term contract opportunity.Start date for the apprenticeship programme is 7th September 2026Where can I find out more?Our Social Media, Follow AstraZeneca on LinkedIn: Inclusion & Diversity: Career Site: These positions are not open to those already educated to Bachelor's degree level or above – for which we have specific Graduate Programmes, see our website for more details #EarlytalentDate Posted12-Jan-2026Closing Date15-Feb-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. Read Less

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