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Astellas Pharma Inc.
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  • Scientific Content Creator  

    Description At Astellas we can offer an inspiring place to work and a... Read More
    Description At Astellas we can offer an inspiring place to work and a chance to make your mark in doing good for others.Our expertise, science and technology make us a pharma company. Our open and progressive culture is what makes us Astellas. It’s a culture of doing good for others and contributing to a sustainable society.Delivering meaningful differences for patients is our driving force. We all have a significant opportunity to make that difference, working locally in the areas we know best, whilst drawing inspiration from the different insights and expertise we have access to globally and from our innovative, external partners.Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity isn’t a buzzword - it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team or division.Our ethos is underpinned by the Astellas Way, comprising five core values: patient focus; ownership; results; openness and integrity.We are proud to offer an inclusive and respectful working environment that fosters collaboration and ownership.Our aspiration is to bring the best brains together, to provide them with world-leading tools and resources and a unique structure that fosters real agility and entrepreneurial spirit.We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. Read Less
  • Clinical Operations Lead (Director) - Oncology  

    Description Clinical Operations Lead (Director) - OncologyAbout Astell... Read More
    Description Clinical Operations Lead (Director) - OncologyAbout Astellas: At Astellas, we are making treatments that matter to people. We are tackling the toughest health challenges, putting the patient at the heart of every move we make. Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity is not a buzzword—it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team, or division. We have developed ground-breaking, innovative medicines in immunology, oncology, and urology. Our medicines are extending and saving the lives of cancer patients, making transplantation possible, and improving the quality of life for those living with conditions where needs are often overlooked. We take a patient-focused approach that allows us to convert brilliant early science into treatments and solutions that directly improve and save patients’ lives. From lab to clinic to patient, we focus on the most promising science, empower the best talent to pursue it, and develop life-changing solutions alongside the best partners. The Opportunity: As a Clinical Operations Lead (Director) at Astellas Pharma, you will play a pivotal role in overseeing the strategic input and operational insights into the asset development planning lifecycle. Your contributions will directly impact the development of innovative therapies that change lives. You will collaborate with cross-functional teams to ensure high-quality deliverables and effective budget management, all while navigating complex regulatory environments. This role reports to the Portfolio Operations Lead, Early Development Clinical Operations and is based in the United Kingdom. Hybrid Working: At Astellas we recognise that our employees enjoy having balance between their professional and home lives. We are proud of our hybrid approach which empowers you to have flexibility on whether to work from home or in the office. Key Responsibilities: Ensuring effective planning, oversight, and execution of Clinical Development Plans and pre/post-POC trials for assigned assets and due diligence projects Providing expert clinical operations strategy input is provided to Primary Focus Area and/or Asset Teams Developing clinical program budgets and resource estimates for assigned assets and due diligence projects Provides oversight of budget and resources during execution of clinical trials Providing oversight and guidance to extended team members in completing program deliverables according to agreed timelines and quality standards, including awareness and escalation of high impact quality-related topics for assigned programs. Providing input on clinical operational matters for interactions with regulatory authorities and key opinion leaders, either globally or regionally, as applicable. Participating in and/or facilitates cross-functional collaboration and strategic problem solving to ensure risk mitigation, appropriate progress and timely completion of trials and deliverables according to established objectives, milestones, and goals. Working with teams to proactively identify and manage operational risks that arise during program and trial conduct, including escalation to Primary Operations Lead, functional management, and external vendor management to accelerate mitigation (as appropriate). Ensuring close collaboration between Early and Late-Stage Clinical Operations Lead(s), including providing strategic and operational input during development and as the assets transition from early to late-stage development Individual can anticipate, recognize and drive problem solving to rapidly address and mitigate emerging program or trial risks. Representing Clinical Operations in inspection readiness activities including coordination of trial team quality deliverables Provide oversight and direction to trial team members for evaluation and implementation of patient-focused strategies for assigned trials. Participating in resource allocation across the department as required for portfolio delivery and non-drug project initiatives/process improvements. Acting as a change champion for Clinical Operations across the global organization Maintaining compliance of direct reports with Astellas policies, procedures, and all associated training. Essential Knowledge & Experience: Significant expertise in early drug development programs (across Phases I-II) executing complex global drug development programs and trials. Demonstrated leadership skills and ability to effectively collaborate with colleagues in Clinical Operations and cross-functionally to deliver on portfolio deliverables and objectives In-depth knowledge of ICH/GCP guidelines and multinational clinical trial regulations. Proven track-record in identifying and leading global process or system improvement initiatives. Must have experience working across multiple phases of development and in multiple therapeutic areas Strong written and verbal communication skills, with fluency in English essential. Preferred Experience:Ability to work flexibly across multiple time zones and travel internationally (up to 25%).Direct people management experience is highly desirable.Education: Bachelor’s degree or equivalentAdditional Information: This is a permanent full-time position. The position is based in the United Kingdom. This position follows our hybrid working model. Role requires a blend of home and a minimum of 1 day per month in our Bourne, London office. Flexibility may be required in line with business needs. Candidates must be located within a commutable distance of the office. We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. Beware of recruitment scams impersonating Astellas recruiters or representatives. Authentic communication will only originate from an official Astellas LinkedIn profile or a verified company email address. If you encounter a fake profile or anything suspicious, report it promptly to LinkedIn's support team through LinkedIn Help. #LI-Addlestone#LI-Hybrid#LI-JU1 Read Less
  • Description Research & Development Strategy LeadAbout Astellas:At Aste... Read More
    Description Research & Development Strategy LeadAbout Astellas:At Astellas we are a progressive health partner, delivering value and outcomes where needed. We pursue innovative science, focussing initially on the areas of greatest potential and then developing solutions where patient need is high, often in rare or under-served disease areas and in life-threatening or life-limiting diseases and conditions. We work directly with patients, doctors and health care professionals on the front line to ensure patient and clinical needs are guiding our development activities at every stage. Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity isn’t a buzzword - it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team or division. We work closely with regulatory authorities and payers to find new ways to ensure access to new therapies. We deliver the latest insights and real-world evidence to inform the best decisions for patients and their care-givers, to ensure the medicines we develop continue to provide meaningful outcomes. Beyond medicines, we support our stakeholder communities to drive initiatives that improve awareness, education, access and ultimately standards of care. The Opportunity:As a R&D Strategy Lead, you will play a pivotal role in shaping Astellas’ research and development strategy. Reporting to the Head of R&D Strategy and Operations, this position serves as a key integrator and facilitator across the CRDO (Chief Research & Development Officer) organization. You will help define and implement strategic roadmaps, manage decision-making bodies, and ensure operational excellence to support Astellas’ long-term innovation agenda.Hybrid Working:At Astellas we recognise the importance of balancing your work and home life, so we offer a hybrid working solution allowing time to connect with colleagues in person at the office alongside the flexibility to work from home; optimising the most productive work environment for you to succeed and deliver.Responsibilities:Act as a thought partner to the CRDO and Head of R&D Strategy and Operations to realize the CRDO vision.Develop and implement research strategic roadmaps aligned with corporate strategic plans (CSP).Provide advisory and PMO services to divisions under CRDO.Manage strategic, organizational, and operational initiatives portfolio.Create and maintain integrated reporting to drive decisions on organizational and project operations.Lead process improvement strategies, IT platforms, and governance frameworks for CRDO divisions.Coach and mentor junior research strategy team member Essential Knowledge & Experience:Strong strategic thinking and ability to partner with senior leadership.Scientific background to credibly engage with research leadership.Business expertise to design and maintain operating models (org structure, budget, talent management).Proven leadership and project management skills.Education:PhD or equivalent advanced degreePreferred Skills & Knowledge:Experience of working in a global organization.Experience in pharmaceutical R&D strategy or operations.Additional information:Type of role: This is a permanent role Location: UKThis role follows a hybrid working model, blending home-based work with a minimum of 1 day per quarter in the office (to be confirmed based on primary location and business need). Flexibility may be required in line with business needs.This position may require occasional international travel.We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.Beware of recruitment scams impersonating Astellas recruiters or representatives. Authentic communication will only originate from an official Astellas LinkedIn profile or a verified company email address. If you encounter a fake profile or anything suspicious, report it promptly to LinkedIn's support team through LinkedIn Help#LI- Addlestone#LI-Hybrid#LI-LG1
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  • Scientist II, Discovery, Frontier Biology  

    Description Scientist II, Discovery, Frontier BiologyAbout Astellas: A... Read More
    Description Scientist II, Discovery, Frontier BiologyAbout Astellas: At Astellas we are a progressive health partner, delivering value and outcomes where needed. We pursue innovative science, focusing initially on the areas of greatest potential and then developing solutions where patient need is high, often in rare or under-served disease areas and in life-threatening or life-limiting diseases and conditions. We work directly with patients, doctors and health care professionals on the front line to ensure patient and clinical needs are guiding our development activities at every stage. Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity isn’t a buzzword - it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team or division. We work closely with regulatory authorities and payers to find new ways to ensure access to new therapies. We deliver the latest insights and real-world evidence to inform the best decisions for patients and their care-givers, to ensure the medicines we develop continue to provide meaningful outcomes. Beyond medicines, we support our stakeholder communities to drive initiatives that improve awareness, education, access and ultimately standards of care. The Opportunity: This role sits at the heart of our drug discovery work, focused on delivering high-quality bench research and running in vitro and/or in vivo assays that directly shape our pipeline. You’ll be hands-on in designing, planning, and executing studies that generate the critical data needed to hit key program milestones. You’ll work closely with a collaborative, cross-functional team, maintaining clear and consistent communication with both internal and external stakeholders to keep programs moving forward. Your responsibilities will include developing, executing, and evaluating in vitro and in vivo study designs to ensure robust, meaningful outcomes. Beyond the lab, you’ll play a key role in leading—or contributing to—research program teams, helping to spark new ideas, build smart study plans, run pharmacology studies, and deliver high-value results on time. This role offers the chance to actively engage with global R&D partners and make a real, visible impact on the progression of new drug candidates. Hybrid Working: At Astellas we recognise the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimise the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines. Responsibilities and Accountabilities: This position directly impacting our ability to prosecuting company goals of maintaining an early-stage pipeline of potential drug candidates. Measures of success including advancing new targets through successive stages of the drug discovery pipeline, with key components including: Efficiently and technically competently executing laboratory work designed to advancing early-stage projects. Being accountable for the timeliness and quality of individual scientific workload. Being accountable for ensuring the integrity of data being generated for scientific projects. Keeping behavioural guidelines in mind while acting as a role model for responsibly adhering to team policies, procedures, and guidelines for conducting work. Accurately interpreting experimental data, performing statistical analyses, formulating conclusions, and communicating data with colleagues. Maintaining accurate and up-to-date records of experimental data. Presenting data at regular internal meetings. Reporting to the manager and program lead.(In some cases)Demonstrating and evolving pharmaceutical capabilities, including generating new ideas, developing target product profiles, applying pharmacology study expertise, and explaining scientific value at a professional level. Exploring cutting-edge technologies and scientific approaches globally and creating new research programs at Astellas through deep understanding of research strategy and high sensitivity to external scientific trends. Organizing teams composed of multiple research programs, ensuring alignment across programs, prioritizing initiatives, allocating resources, and scheduling team timelines. Entirely and independently leading research program teams by planning actions, conducting pharmacological research, achieving schedules, and actively engaging with stakeholders across R&D, global Astellas divisions, and external partners to creating high-value candidates or products. Essential Knowledge & Experience: Proficiency in cell handling and tissue culture techniques. Strong background in molecular biology, including DNA, RNA, and protein-related methodologies. Competence in designing, developing, and executing wide range of in vitro assays and/or in vivo animal models. Demonstrated experience in assay development, particularly for novel entities or targets. Skilled in in vivo tissue processing and biological sample analysis. In-depth understanding of pharmacology, particularly in non-clinical drug discovery research settings. Proven ability to work collaboratively within a multidisciplinary team environment. Strong organizational, time management, and problem-solving skills with scientific attention to detail. Able to work productively and to participate in a highly creative and fast-paced environment. Excellent communication and interpersonal skills. Preferred Knowledge & Experience: Master’s degree (MS) or Doctor of Philosophy (PhD) in relevant scientific field that provides knowledge of theories, principles and concepts within biological sciences or equivalent.Drug discovery experience in multiple disease areas, such as oncology and Immunology. A strong track record of contributing to successful drug discovery and development projects. Experience with cutting-edge molecular biology techniques. Deep understanding of in vivo disease models. Experience in the development and validation of non-clinical pharmacological models. Candidates with experience in antibody research, synthetic biology, or protein engineering will be a plus. Ability to process and interpret complex datasets and provide actionable insights. Ability to manage multiple projects simultaneously and prioritize tasks effectively. Proven ability to collaborate with cross-functional teams, including pharmacologists, chemists, and clinical researchers in multi-regional team. Additional Information: The is a permanent full-time field-based role based in the UK. This position follows our hybrid working model. The role requires a blend of home and a minimum of 4 days a week in office in our Cambridge office. Flexibility may be required in line with business needs. Candidates must be located within a commutable distance of the office. We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. Beware of recruitment scams impersonating Astellas recruiters or representatives. Authentic communication will only originate from an official Astellas LinkedIn profile or a verified company email address. If you encounter a fake profile or anything suspicious, report it promptly to LinkedIn's support team through LinkedIn Help. #LI-Cambridge#LI-Hybrid#LI-LG1 Read Less
  • Description Senior Research Associate, Discovery, Frontier BiologyAbou... Read More
    Description Senior Research Associate, Discovery, Frontier BiologyAbout Astellas: At Astellas we are a progressive health partner, delivering value and outcomes where needed. We pursue innovative science, focusing initially on the areas of greatest potential and then developing solutions where patient need is high, often in rare or under-served disease areas and in life-threatening or life-limiting diseases and conditions. We work directly with patients, doctors and health care professionals on the front line to ensure patient and clinical needs are guiding our development activities at every stage. Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity isn’t a buzzword - it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team or division. We work closely with regulatory authorities and payers to find new ways to ensure access to new therapies. We deliver the latest insights and real-world evidence to inform the best decisions for patients and their care-givers, to ensure the medicines we develop continue to provide meaningful outcomes. Beyond medicines, we support our stakeholder communities to drive initiatives that improve awareness, education, access and ultimately standards of care. The Opportunity: The primary focus of this role is to deliver high-quality bench research and to design and execute in vitro and/or in vivo assays that directly support our drug discovery programmes. You will work closely with the broader team to drive program goals forward, maintaining clear and ongoing communication with both internal and external stakeholders. The role also involves planning and conducting in vitro and in vivo studies to generate critical data aligned with key program milestones.In addition, you will be responsible for the development, execution, and evaluation of in vitro and in vivo study designs to ensure robust, meaningful outcomes. Hybrid Working: At Astellas we recognise the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimise the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines. Responsibilities and Accountabilities: This position directly impacting our ability to prosecuting company goals of maintaining an early-stage pipeline of potential drug candidates. Measures of success including advancing new targets through successive stages of the drug discovery pipeline, with core components including: Efficiently and competently executing laboratory work designed to advancing early-stage projects. Being accountable for the timeliness and quality of individual scientific workload. Being accountable for ensuring the integrity of data being generated for scientific projects. Keeping behavioural guidelines in mind while acting as a role model for responsibly adhering to team policies, procedures, and guidelines for conducting work. Accurately interpreting experimental data, performing statistical analyses, formulating conclusions, and communicating findings with colleagues. Maintaining accurate and up-to-date records of experimental data. Presenting data at regular internal meetings. Reporting to the manager and program lead. Essential Knowledge & Experience: Solid experience required in drug discovery experience. Proficiency in cell handling and tissue culture techniques. Background in oncology drug discovery research, including DNA, RNA, and protein-related methodologies. Competence in designing, developing, and executing wide range of in vitro assays and/or in vivo animal models. Demonstrated experience in assay development, particularly for novel entities or targets. Skilled in in vivo tissue processing and biological sample analysis. In-depth understanding of pharmacology, particularly in non-clinical drug discovery research settings. Proven ability to work collaboratively within a multidisciplinary team environment. Strong organizational, time management, and problem-solving skills with scientific attention to detail. Able to work productively and to participate in a highly creative and fast-paced environment. Excellent communication and interpersonal skills. Preferred Knowledge & Experience: Bachelor’s degree (BS), Master’s degree (MS) or Doctor of Philosophy (PhD) in relevant scientific field that provides knowledge of theories, principles and concepts within biological sciences or equivalent. Knowledge of drug discovery processes coupled with relevant industry experience, particularly in a pharmaceutical or biotech company setting. Drug discovery experience in multiple disease areas, such as oncology and Immunology. Experience with molecular biology techniques and/or in vivo disease models. Experience in the development and validation of non-clinical pharmacological models. Candidates with experience in antibody research, synthetic biology, or protein engineering will be a plus. Ability to process and interpret complex datasets and provide actionable insights. Additional Information: The is a permanent full-time field-based role based in the UK. This position follows our hybrid working model. The role requires a blend of home and a minimum of 4 days a week in office in our Cambridge office. Flexibility may be required in line with business needs. Candidates must be located within a commutable distance of the office. We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. Beware of recruitment scams impersonating Astellas recruiters or representatives. Authentic communication will only originate from an official Astellas LinkedIn profile or a verified company email address. If you encounter a fake profile or anything suspicious, report it promptly to LinkedIn's support team through LinkedIn Help.#LI-Cambridge#LI-Hybrid#LI-LL1 Read Less
  • Digital Health Solutions Lead  

    Description Digital Health Solutions Lead (UK)About Astellas:At Astell... Read More
    Description Digital Health Solutions Lead (UK)
    About Astellas:At Astellas we are a progressive health partner, delivering value and outcomes where needed. We pursue innovative science, focusing initially on the areas of greatest potential and then developing solutions where patient need is high, often in rare or under-served disease areas and in life-threatening or life-limiting diseases and conditions. We work directly with patients, doctors and health care professionals on the front line to ensure patient and clinical needs are guiding our development activities at every stage. Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity isn’t a buzzword - it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team or division. We work closely with regulatory authorities and payers to find new ways to ensure access to new therapies. We deliver the latest insights and real-world evidence to inform the best decisions for patients and their caregivers, to ensure the medicines we develop continue to provide meaningful outcomes. Beyond medicines, we support our stakeholder communities to drive initiatives that improve awareness, education, access and ultimately standards of care. The Opportunity: This is a technical leadership position, accountable for the definition, oversight, and operational execution of Data Management (DM) deliverables for the Quantitative Sciences and Evidence Generation (QSEG) eCOA/eSource Team. This may include clinical study and program level deliverables for eCOA, and for eSource capabilities, such as wearables, Electronic Health Records (EHRs), applications (apps), eConsent, etc. In this role, you will be responsible to provide operational leadership for eCOA and eSource deliverables, and to lead process oversight for clinical study and program level implementation. This includes responsibility for project management and technical leadership for the end-to-end study phases of setup, conduct, and closeout. This role drives operational excellence, global regulatory compliance, training and technology vendor process oversight for all DHT study level solutions and activities. Hybrid Working: At Astellas we recognize the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimize the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines. Key Activities For This Role: Execution of eCOA and eSource process capabilities at a study, program, and enterprise level. This may include oversight and process ownership for the following: vendor deliverables and timelines, defining data collection, reporting and mapping requirements, establishing study level dataflow, technology/app and device deployment, testing, dataflow and data change oversight and archival activities. Establish process for cross-functional coordination for eCOA/eSource implementation in collaboration with study teams, eCOA/eSource service provider(s), translations providers, and COA Specialist. Organize eCOA/eSource related meetings with vendors and study teams in accordance with Astellas processes Oversight of risk assessments and mitigation strategies to ensure on-time delivery of eCOA and eSource capabilities Provide operational process oversight for eCOA/eSource vendors (Has a broad understanding of how source data come together, and/or how system vendors and solutions function to support the execution of the study) Have a comprehensive understanding and application of eSource principles and regulations and represents data standards, quality, and inspection readiness interests with key stakeholders and study teams. Ensure adherence with best practices, operational playbooks, guidance documents, SOPs, work practice documents, tools, databases, and standard templates for eCOA and eSource. Responsible for ensuring that all supporting operational documentation for studies/systems is maintained in accordance with processes to ensure quality, traceability, and regulatory compliance. Lead process improvement activities that support operational efficiencies. Provides feedback and recommendations for operational governance discussions with key eCOA and eSource technology vendors. Maintain a strong network of contacts both within and outside of Astellas to further develop breadth and depth of knowledge. Stays abreast of industry developments. Plays a leadership role in industry or professional organizations. Develops and maintains relationships with peers in the industry. Essential Knowledge & Experience: Demonstrated previous experience in pharma or CRO industry in either an eCOA or relevant Data Management role. Seasoned expert with eCOA implementation and experience with eSource solutions implementation (wearables, eConsent, videography, EHR to EDC, etc.) Demonstrated knowledge of the Clinical Development Process Clinical Trial Process - understanding of the clinical trial study process (e.g., data standards, regulations, guidelines, delivery of data to audiences, drug development/RBQM components, etc.) Vendor Landscape - working knowledge of pharmaceutical vendors/CROs and how they are used to execute on Data Science activities Analytical systems - understanding of and experience with central monitoring systems, Elluminate, reporting and visualization tools, etc. Data management - deep understanding of the data management process, lifecycle and key activities (e.g., ETL, data quality, knowledge of database systems, etc.). Data types - understanding of and experience with different data types (e.g., audit trail review, eCOA, EDC, External, Labs, etc.) Project Management - identifies and communicates project goals, timelines, and milestones; identifies project interdependencies and potential constraints; assigns roles and holds stakeholders accountable to meet project outcomes on time and within budget Stakeholder/Team Management & Alignment - understands and clearly communicates the goals of internal teams and external stakeholders (i.e., vendors), and their expected impact to the project/study; ensures they meet their goals and expectations; ensures cross-functional and cross-divisional collaboration; shows ability to deliver through others. Demonstrated active contribution to inspections and major (vendor) audits. Expert knowledge of local and international regulations for clinical trials (e.g., GCP). Expert level understanding of data integrity principles and other associated industry and regulatory level best practices and requirements. Excellent verbal and written communication skills. Demonstrated learning agility, ability to rapidly adopt new technologies for Data Management. Proven ability to work with and influence individuals across multiple disciplines and organizational levels in international environment. Preferred Experience: Professional certification in a Clinical Development discipline Demonstrated mastery of relevant DM skills (e.g., defining data collection requirements, applying data integrity principles, database design, dataflow etc.) in multiple drug development programs, inclusive of all activities from program inception to regulatory submission. Education: BS in Computer Science, Informatics, or life science discipline Additional Information:This is a permanent, full-time position, based in the United Kingdom. This position follows our hybrid working model. Role requires a blend of home and minimum once a quarter in office. Flexibility may be required in line with business need. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. Beware of recruitment scams impersonating Astellas recruiters or representatives. Authentic communication will only originate from an official Astellas LinkedIn profile or a verified company email address. If you encounter a fake profile or anything suspicious, report it promptly to LinkedIn's support team through LinkedIn Help. #LI-Addlestone #LI-Hybrid #LI-LL1 Read Less
  • Direct Tax Lead - EMEA  

    Description Direct Tax Lead - EMEAAbout Astellas: At Astellas we are a... Read More
    Description Direct Tax Lead - EMEAAbout Astellas: At Astellas we are a progressive health partner, delivering value and outcomes where needed. We pursue innovative science, focusing initially on the areas of greatest potential and then developing solutions where patient need is high, often in rare or under-served disease areas and in life-threatening or life-limiting diseases and conditions. We work directly with patients, doctors and health care professionals on the front line to ensure patient and clinical needs are guiding our development activities at every stage. Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity isn’t a bussword - it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team or division. We work closely with regulatory authorities and payers to find new ways to ensure access to new therapies. We deliver the latest insights and real-world evidence to inform the best decisions for patients and their care-givers, to ensure the medicines we develop continue to provide meaningful outcomes. Beyond medicines, we support our stakeholder communities to drive initiatives that improve awareness, education, access and ultimately standards of care. The Opportunity: As the Direct Tax Lead, EMEA, who is a senior tax professional, you will be responsible for all direct tax compliance, reporting, risk management, and strategy across the region. You will support the EMEA Controller & Head of Tax and leading a team of three, manage quarterly tax reporting, consolidation of financial data and alignment with global policies in a fast-paced, collaborative environment. Your role requires strong technical expertise, the ability to explain complex tax matters clearly and experience working across a matrixed organisation. Your role also drives process, data, and governance improvements using analytics and technology, while managing relationships with HMRC and other tax authorities. You’ll help shape best-in-class tax compliance, reporting, and controversy management, and act as a subject matter expert to finance teams across EMEA on statutory accounts, reporting requirements, and best practices. Hybrid Working: At Astellas we recognise the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimise the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines. Responsibilities and Accountabilities: Aligning Strategy, Policy & Tax Law: You are implementing global tax standards, developing local strategies that support business goals, minimising exposure, and staying updated on international tax law changes, treaties, and withholding taxes while proactively advising the business and collaborating with global tax colleagues. Leading International & Cross-Border Projects: You are leading tax input on cross-border work, including mergers, acquisitions, restructurings, new product launches, lifecycle changes, and divestments, ensuring all international tax impacts are fully considered. Managing Compliance, Reporting & Audit: You are managing all EMEA direct tax compliance, statutory and consolidated reporting, CbCr and Pillar 2 requirements, overseeing external providers, reviewing contract effectiveness, preparing tax accounting papers and audit memos, supporting statutory compliance, and driving regional standardisation and efficiency. Strengthening Risk, Controls & Governance: You are identifying and managing tax risks such as PE and CFCs, monitoring compliance exposures, enhancing tax processes, controls, and JSOX requirements, and using technology and AI to improve governance, efficiency, and risk management. Building Relationships, Leading Teams & Managing Budgets: You are building strong relationships with auditors, advisors, tax authorities, finance teams, and business partners, mentoring a high-performing tax team, and managing EMEA tax budgets effectively. Mandatory Compliance requirements You are staying aware of Astellas’ Group Code of Conduct, policies, procedures, and all applicable laws and regulations. You are seeking clarification and guidance when needed and raising concerns promptly with the appropriate manager, including the Ethics and Compliance Team when relevant. You are completing all mandatory Ethics and Compliance training on time to maintain up-to-date awareness. You are also following the Astellas Way, expected competencies, and all HR policies, procedures, and behavioural standards. Required Experience: Qualifications & Technical Expertise: Fluency in English; ACA/ACCA (or equivalent) with CTA preferred. Strong UK, international and OECD tax knowledge, including Pillar 2, BEPS, transfer pricing, tax incentive regimes, and cross-border compliance. Solid understanding of IFRS and tax accounting standards.Experience & Background: Extensive post-qualification experience in international tax within multinational organisations and global accounting/tax firms. Strong UK tax exposure, extensive experience with JSOX environments, and a track record managing complex UK tax audits, EMEA-wide authorities, and statutory tax reporting across large multi-entity groups.Compliance, Reporting & Analytics: Proven ability managing tax compliance, reporting, planning, and audit processes to tight deadlines. Experienced in tax financial reporting consolidation (20+ entities), external audit coordination, and interpreting data, analytics, and insights to support decision-making.Leadership, Stakeholder Management & Ways of Working: Demonstrated success leading and developing teams, managing stakeholders at all levels, and building trusted relationships with finance, business partners, external auditors, and tax authorities. Strong communication skills, professional presence, and the ability to work independently in a fast-paced multinational environment.Innovation, Problem-Solving & Continuous Improvement: Experienced in change management, process improvement, automation, and leveraging innovations such as AI. Detail-driven, organised, proactive, budget-conscious, and able to develop solutions using internal knowledge and strategic thinking.Preferred Qualification: Experience within the pharmaceutical, life science industry or other highly regulated industries Good awareness and experience of other taxes including Employment Taxes, Customs Duties and Indirect TaxesEducation:Degree/Advanced degreeAdditional Information: This is a permanent, full-time role based in the UK. Peer group: Americas tax team, Global tax team, Global Capability Centres (in Mexico, Poland and India), local Affiliate Controllers, Global Financial Services, Commercial Finance, Tax, Treasury and Corporate AccountingThis position follows our hybrid working model. The role requires a blend of home and a minimum of 2 days a week in office in our Addlestone office. Flexibility may be required in line with business needs. Candidates must be located within a commutable distance of the office. We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. Beware of recruitment scams impersonating Astellas recruiters or representatives. Authentic communication will only originate from an official Astellas LinkedIn profile or a verified company email address. If you encounter a fake profile or anything suspicious, report it promptly to LinkedIn's support team through LinkedIn Help. #LI-Addlestone#LI-Hybrid Read Less
  • Description Lead, Global Market Access & Pricing, Women's Health (Seni... Read More
    Description Lead, Global Market Access & Pricing, Women's Health (Senior Director)About Astellas: At Astellas we are a progressive health partner, delivering value and outcomes where needed. We pursue innovative science, focussing initially on the areas of greatest potential and then developing solutions where patient need is high, often in rare or under-served disease areas and in life-threatening or life-limiting diseases and conditions. We work directly with patients, doctors and health care professionals on the front line to ensure patient and clinical needs are guiding our development activities at every stage. Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity isn’t a buzzword - it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team or division. We work closely with regulatory authorities and payers to find new ways to ensure access to new therapies. We deliver the latest insights and real-world evidence to inform the best decisions for patients and their care-givers, to ensure the medicines we develop continue to provide meaningful outcomes. Beyond medicines, we support our stakeholder communities to drive initiatives that improve awareness, education, access and ultimately standards of care. The Opportunity: As the Lead, Global Market Access and Pricing – Women’s Health (Senior Director), you will be responsible for the world-wide market access and pricing strategy for the product. You will develop and drive execution of the Global Market Access and Pricing Brand Strategy through leading a multi-disciplinary Value Access Strategy Team in co-creation of a best-in-industry value position strategy which optimizes product payer leverage points through tailored and where needed innovative payer solutions. The role will report into the Head of Global Market Access Strategic Brands and will work closely with other key cross functional partners across the region. Hybrid Working: At Astellas we recognise the importance of balancing your work and home life, so we offer a hybrid working solution allowing time to connect with colleagues in person at the office alongside the flexibility to work from home; optimising the most productive work environment for you to succeed and deliver. Key Responsibilities: Represent Global Market Access &VAST perspective on payer needs as a core member of the Asset Maximization Team and Global Co-creation Team and impact Commercialisation and evidence generation strategy in alignment with AMT co-leads to optimise brand value under consideration of reimbursement & pricing requirements and dynamics.Lead the development and implementation of innovative pricing and reimbursement strategies using value-based methodologies that both capture optimal product value and support commercial strategy/product positioning for new indications.Develop global value story and global value dossier based on insights collated, identify areas needing Medical Affairs, Value Evidence, Clinical Development and Statistics input and seek analyses and evidence generation accordingly.Define the payer value requirements for the evidence generation plan throughout the lifecycle of the product, identify areas needing MA & VE input and execution in evidence generation plans and establish alignment with critical functions such as Regulatory, Clinical Development, Stats team and the co-creation and sub co-creation Markets and endorsement by senior leadership. Work collaboratively with MA/VE and Commercial and Development Leads at Global, Area and Affiliate level to deliver integrated Evidence Generation Plan (iEGP), Brand Market Access Strategic Plan, ensuring it is embedded within the integrated Global Brand Plan, Core Medical Plans and Global & regional development plans, and that customer-relevant Global Brand Value Plans are developed and delivered. Lead the Value Access Strategy Team (VAST) and represent GMAx and VAST on the Asset Maximization Team (AMT) and Global Co-creation team (GCT). Essential Knowledge & Experience: Proven experience in a regional / global market access position within a global pharmaceutical organization. Experience across Market Access, Reimbursement or HEOR experience in the pharmaceutical industry with a proven track record of strategy development and execution. Strong understanding and experience of working within different payer environments and drivers for reimbursement, value-based access, and how to integrate into drug development and commercial strategies. Deep knowledge / scientific background on the assigned therapy area – women’s health will be highly preferred. Leadership skills and demonstrated ability to work effectively / influence without authority throughout the organization and on a global basis. Strong written and verbal communication in English. Preferred Experience: Strong interpersonal, communication & collaboration skills working cross-functionally within matrix structures. Education: Post-graduate qualification such as MBA and/or MSc or equivalent. Additional information: This is a full time, permanent position. The role is based out of Addlestone, UK or could be based in the Nordic countries or the NetherlandsThis position follows our hybrid working model. Role requires a blend of home and a minimum of 1 day per quarter in our Addlestone office. Flexibility may be required in line with business needs. What We Offer:A challenging and diversified job in an international setting.Opportunity and support for continuous development.Inspiring work climate. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. Beware of recruitment scams impersonating Astellas recruiters or representatives. Authentic communication will only originate from an official Astellas LinkedIn profile or a verified company email address. If you encounter a fake profile or anything suspicious, report it promptly to LinkedIn's support team through LinkedIn Help#LI-Addlestone#LI-Hybrid Read Less

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Astrid-Lindgren-Weg 12 38229 Salzgitter Germany